Objective Depression is among the most pervasive and debilitating neuropsychiatric
sequelae experienced by patients following a traumatic brain injury (TBI). While the …

While Huntington disease (HD) is caused solely by a polyglutamine expansion in the
huntingtin gene, environmental factors can influence HD onset and progression. Here, we …

Introduction The analysis of the role of the mitochondria in oxidative damage and skin aging
has been a significant aspect of dermatological research. Mitochondria generate most …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease. It is
caused by the expansion of the CAG trinucleotide repeat sequence in the HTT gene. HD …

Anti-neuroinflammatory treatment has gained importance in the search for pharmacological
treatments of different neurological and psychiatric diseases, such as depression …

Circulating cell-free mitochondrial DNA (ccf-mtDNA) is a biomarker of cellular injury or
cellular stress and is a potential novel biomarker of psychological stress and of various …

Synapses serve as the points of communication between neurons, consisting primarily of
three components: the presynaptic membrane, synaptic cleft, and postsynaptic membrane …

Background Glucocorticoid (GR) and mineralocorticoid (MR) receptors are highly expressed
in cardiac tissue, and both can be activated by corticosteroids. MR activation, in acute …

Diabetic cognitive impairment (DCI) is a common diabetic complication characterized by
learning and memory deficits. In diabetic patients, hyperactivated hypothalamic-pituitary …

The developing and adult brain is a target organ for the vast majority of hormones produced
by the body, which are able to cross the blood–brain barrier and bind to their specific …