Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …

Conjugation is the process by which bacteria exchange genetic materials in a unidirectional
manner from a donor cell to a recipient cell. The discovery of conjugation signalled the dawn …

Conjugation is a contact-dependent mechanism for the transfer of plasmid DNA between
bacterial cells, which contributes to the dissemination of antibiotic resistance. Here, we use …

The F plasmid or F-factor is a large, 100-kbp, circular conjugative plasmid of Escherichia coli
and was originally described as a vector for horizontal gene transfer and gene …

Conjugation, the process by which plasmid DNA is transferred from one bacterium to
another, is mediated by type IV secretion systems (T4SSs). T4SSs are versatile systems that …

The tra operon of the prototypical F plasmid and its relatives enables transfer of a copy of the
plasmid to other bacterial cells via the process of conjugation. Tra proteins assemble to form …

Relaxases play essential roles in conjugation, the main process by which bacteria exchange
genetic material, notably antibiotic resistance genes. They are bifunctional enzymes …

Replication-initiating HUH endonucleases (Reps) are sequence-specific nucleases that
cleave and rejoin single-stranded DNA (ssDNA) during rolling-circle replication. These …

Efficient in silico development of novel antibiotics requires high-resolution, dynamic models
of drug targets. As conjugation is considered the prominent contributor to the spread of …

Bacterial transformation, transduction, and “conjugation” can be considered the first
horizontal transfer mechanisms in living organisms; these mechanisms have occurred since …