Fox transcription factors: from development to disease

ML Golson, KH Kaestner - Development, 2016 - journals.biologists.com
Forkhead box (Fox) transcription factors are evolutionarily conserved in organisms ranging
from yeast to humans. They regulate diverse biological processes both during development …

The ontogenesis of language lateralization and its relation to handedness

S Ocklenburg, C Beste, L Arning, J Peterburs… - Neuroscience & …, 2014 - Elsevier
Dominance of the left hemisphere for many aspects of speech production and perception is
one of the best known examples of functional hemispheric asymmetries in the human brain …

Convergent repression of Foxp2 3′ UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons

YM Clovis, W Enard, F Marinaro, WB Huttner… - …, 2012 - journals.biologists.com
MicroRNAs (miRNAs) are rapidly emerging as a new layer of regulation of mammalian brain
development. However, most of the miRNA target genes remain unidentified. Here, we …

The role of forkhead box family in bone metabolism and diseases

J Xu, K Wang, Z Zhang, D Xue, W Li… - Frontiers in …, 2022 - frontiersin.org
Forkhead box (Fox) family, an evolutionarily conserved family of transcription factors
carrying the “Forkhead” motif, plays an indispensable role in human health and disease. Fox …

Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization

C Sin, H Li, DA Crawford - Journal of Molecular Neuroscience, 2015 - Springer
Abstract FOXP1, FOXP2, and FOXP4 are three members of the FOXP gene subfamily of
transcription factors involved in the development of the central nervous system. Previous …

The Fox/Forkhead transcription factor family of the hemichordate Saccoglossus kowalevskii

JH Fritzenwanker, J Gerhart, RM Freeman, CJ Lowe - EvoDevo, 2014 - Springer
Abstract Background The Fox gene family is a large family of transcription factors that arose
early in organismal evolution dating back to at least the common ancestor of metazoans and …

Language development and disorders: Possible genes and environment interactions

L Onnis, A Truzzi, X Ma - Research in developmental disabilities, 2018 - Elsevier
Abstract Language development requires both basic cognitive mechanisms for learning
language and a rich social context from which learning takes off. Disruptions in learning …

Differential song deficits after lentivirus-mediated knockdown of FoxP1, FoxP2, or FoxP4 in area X of juvenile zebra finches

P Norton, P Barschke, C Scharff… - Journal of …, 2019 - Soc Neuroscience
Mutations in the transcription factors FOXP1 and FOXP2 are associated with speech
impairments. FOXP1 is additionally linked to cognitive deficits, as is FOXP4. These FoxP …

Transcription Factor Forkhead Box P (Foxp) 1 Reduces Brain Damage During Cerebral Ischemia–Reperfusion Injury in Mice Through FUN14 Domain-containing …

Y Li, Y Changhong, Y Liyu, M Changchang, L Zeng… - Neuroscience, 2023 - Elsevier
Mitophagy plays a significant role in modulating the activation of pyrin domain-containing
protein 3 (NLRP3) inflammasome, which is a major contributor to the inflammatory response …

A proposed neurological interpretation of language evolution

A Ardila - Behavioural Neurology, 2015 - Wiley Online Library
Since the very beginning of the aphasia history it has been well established that there are
two major aphasic syndromes (Wernicke's‐type and Broca's‐type aphasia); each one of …