Laser interstitial thermal therapy (LITT) guided by magnetic resonance imaging (MRI) is a
new treatment option for patients with brain and non‐central nervous system (non‐CNS) …

Background Acute myeloid leukemia (AML) is a hematological malignancy due to
anomalous differentiation and proliferation of hematopoietic stem cells with myeloid blast …

Therapy-related myelodysplastic syndromes (t-MDS) represent a heterogeneous group of
malignancies that arise as a late complication of prior exposure to chemotherapy and/or …

E-selectin, a cytoadhesive glycoprotein, is expressed on venular endothelial cells and
mediates leukocyte localization to inflamed endothelium, the first step in inflammatory cell …

Lipid nanoparticles (LNPs) are biocompatible drug delivery systems that have found
numerous applications in medicine. Their versatile nature enables the encapsulation and …

Simple Summary The concept of targeted drug delivery (TDD) represents an innovative and
effective treatment approach, which was developed with an attempt to minimize damage …

PURPOSE There are significant disparities in care and outcomes for patients with leukemias
and multiple myeloma (MM). To evaluate the extent to which clinical trials (CTs) match the …

Acute myeloid leukemia (AML) secondary to antecedent hematologic disorder or prior
therapeutics for cancer represent a diverse group of leukemias often associated with inferior …

Abstract CPX-351 (Europe: Vyxeos® liposomal; United States: Vyxeos®) is a dual-drug
liposomal encapsulation of daunorubicin and cytarabine in a synergistic 1: 5 molar ratio. In a …

Objective to review the current diagnostic and therapeutic landscape of AML in Latin
America as a reflection of other low-and middle-income countries and regions of the world …