siRNA drug delivery across the blood–brain barrier in Alzheimer's disease
MI Sajid, FS Sheikh, F Anis, N Nasim… - Advanced Drug Delivery …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a few FDA-
approved drugs that provide modest symptomatic benefits and only two FDA-approved …
approved drugs that provide modest symptomatic benefits and only two FDA-approved …
Nanotechnology-based gene therapy as a credible tool in the treatment of Alzheimer's disease
Toxic aggregated amyloid-β accumulation is a key pathogenic event in Alzheimer's disease.
Treatment approaches have focused on the suppression, deferral, or dispersion of amyloid …
Treatment approaches have focused on the suppression, deferral, or dispersion of amyloid …
Protein and gene delivery systems for neurodegenerative disorders: where do we stand today?
It has been estimated that every year, millions of people are affected by neurodegenerative
disorders, which complicate their lives and their caregivers' lives. To date, there has not …
disorders, which complicate their lives and their caregivers' lives. To date, there has not …
Modeling the blood-brain barrier for treatment of central nervous system (CNS) diseases
O Rice, A Surian, Y Chen - Journal of Tissue Engineering, 2022 - journals.sagepub.com
The blood-brain barrier (BBB) is the most specialized biological barrier in the body. This
configuration of specialized cells protects the brain from invasion of molecules and particles …
configuration of specialized cells protects the brain from invasion of molecules and particles …
Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials
D Huang, W Liao, J Li, T Chen, X Wang… - Advanced Functional …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that
constitutes the third most common cause of death among elderly individuals. AD patients …
constitutes the third most common cause of death among elderly individuals. AD patients …
Emerging two-dimensional materials-based diagnosis of neurodegenerative diseases: Status and challenges
Neurodegenerative diseases (NDs), conventionally characterized by multifarious impacts on
patients' cognitive skill, motor function and memory, have been brought into focus with the …
patients' cognitive skill, motor function and memory, have been brought into focus with the …
[HTML][HTML] siRNA therapeutics: future promise for neurodegenerative diseases
A Amiri, G Barreto, T Sathyapalan… - Current …, 2021 - ncbi.nlm.nih.gov
Neurodegenerative diseases (ND), as a group of central nervous system (CNS) disorders,
are among the most prominent medical problems of the 21 st century. They are often …
are among the most prominent medical problems of the 21 st century. They are often …
Emerging paradigms in Alzheimer's Therapy
K Rajendran, AJ Sukumar, UM Krishnan - European Journal of …, 2024 - Elsevier
Alzheimer's disease is a neurodegenerative disorder that affects elderly, and its incidence is
continuously increasing across the globe. Unfortunately, despite decades of research, a …
continuously increasing across the globe. Unfortunately, despite decades of research, a …
A potential nine-lncRNAs signature identification and nomogram diagnostic model establishment for papillary thyroid cancer
JM Yao, JY Zhao, FF Lv, XB Yang… - Pathology and Oncology …, 2022 - por-journal.com
The purpose of our current study was to establish a long non-coding RNA (lncRNA)
signature and assess its prognostic and diagnostic power in papillary thyroid cancer (PTC) …
signature and assess its prognostic and diagnostic power in papillary thyroid cancer (PTC) …
Advanced molecular therapies for neurological diseases: focus on stroke, alzheimer's disease, and parkinson's disease
M Katta, BA Mathew, P Chaturvedi, A Ludhiadch… - Neurological …, 2023 - Springer
Neurological diseases (NDs) are one of the leading causes of disability and the second
leading cause of death globally. Among these stroke, Alzheimer's disease (AD), and …
leading cause of death globally. Among these stroke, Alzheimer's disease (AD), and …