The International Liaison Committee on Resuscitation has initiated a continuous review of
new, peer-reviewed, published cardiopulmonary resuscitation science. This is the third …

Objective: The management of hypoxemia in critically ill patients is challenging. Whilst the
harms of tissue hypoxia are well recognized, the possibility of harm from excess oxygen …

Perinatal asphyxia-induced brain injury may present as hypoxic-ischemic encephalopathy in
the neonatal period, and disability including cerebral palsy in the long term. The brain injury …

Rationale: Pure oxygen causes more oxidative stress than room air in resuscitation of
asphyctic neonates, and consequently could be associated with increased tissue damage …

An increasing body of evidence has revealed that interventions performed during
resuscitation of extremely-low-gestational-age neonates (ELGANs) may have a direct …

Mitochondrial dysfunction is the most fundamental mechanism of cell damage in cerebral
hypoxia‐ischemia and reperfusion. Mitochondrial respiratory chain (MRC) is increasingly …

Fetal cerebrovascular responses to acute hypoxia are fundamentally different from those
observed in the adult cerebral circulation. The magnitude of hypoxic vasodilatation in the …

Education in oxygenation and in how oxygen is given to newborns needs to increase.
Treatment with oxygen should no longer be considered proverbial and customary …

Newborn resuscitation with pure oxygen may be associated with long-term detrimental
effects. Due to the change in attitude toward use of less oxygen upon resuscitation, there is a …

Background: In Africa, the clinical syndrome of pneumonia remains the leading cause of
morbidity and mortality in children in the post-neonatal period. This represents a significant …