Immature renal dendritic cells (DCs) are protective early in murine crescentic GN, but the
mechanisms underlying this protection are unknown. Here, depletion of DCs reduced the …

ADAM10 and ADAM17 have been shown to contribute to the acquired drug resistance of
HER2-positive breast cancer in response to trastuzumab. The majority of ADAM10 and …

Objective Atherosclerosis disease is a leading cause for mortality and morbidity. The
narrowing/rupture of a vulnerable atherosclerotic plaque is accountable for acute …

Background Scavenger receptors play a significant role in clearing aged proteins from the
plasma, including the large glycoprotein coagulation factors von Willebrand factor (VWF) …

Non-alcoholic fatty liver disease (NAFLD), characterised by early lipid accumulation and
subsequent inflammation in the liver, is becoming a worldwide challenge due to its …

Rheumatoid arthritis (RA) is a chronic progressive autoimmune disease leading to
considerable disability over time. The disease can be characterized by the presence of …

Background Soluble CXC chemokine ligand 16 (CXCL16), a scavenger receptor for
oxidized low density lipoprotein, has been shown to promote atherogenic effects in vivo and …

Background The importance of the Notch signaling in the development of glomerular
diseases has been recently described. Therefore we analyzed in podocytes the expression …

Besides its involvement in blood and bone physiology, the kidney's main function is to filter
substances and thereby regulate the electrolyte composition of body fluids, acid-base …

Eur J Clin Invest 2011; 41 (8): 836–845 Abstract Background C‐X‐C chemokine ligand 16
(CXCL16) is a scavenger receptor for oxidized low‐density lipoprotein that has been shown …