Insecticide resistance in mosquitoes: impact, mechanisms, and research directions

N Liu - Annual review of entomology, 2015 - annualreviews.org
Mosquito-borne diseases, the most well known of which is malaria, are among the leading
causes of human deaths worldwide. Vector control is a very important part of the global …

Vector biology meets disease control: using basic research to fight vector-borne diseases

WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Pyrethroid resistance in Aedes aegypti and Aedes albopictus: Important mosquito vectors of human diseases

LB Smith, S Kasai, JG Scott - Pesticide biochemistry and physiology, 2016 - Elsevier
Aedes aegypti and A. albopictus mosquitoes are vectors of important human disease
viruses, including dengue, yellow fever, chikungunya and Zika. Pyrethroid insecticides are …

[HTML][HTML] The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance

W Dermauw, T Van Leeuwen - Insect biochemistry and molecular biology, 2014 - Elsevier
About a 100 years ago, the Drosophila white mutant marked the birth of Drosophila genetics.
The white gene turned out to encode the first well studied ABC transporter in arthropods …

Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods

R Feyereisen, W Dermauw, T Van Leeuwen - Pesticide biochemistry and …, 2015 - Elsevier
The recent accumulation of molecular studies on mutations in insects, ticks and mites
conferring resistance to insecticides, acaricides and biopesticides is reviewed. Resistance is …

[HTML][HTML] Impact of environment on mosquito response to pyrethroid insecticides: facts, evidences and prospects

TE Nkya, I Akhouayri, W Kisinza, JP David - Insect biochemistry and …, 2013 - Elsevier
By transmitting major human diseases such as malaria, dengue fever and filariasis,
mosquito species represent a serious threat worldwide in terms of public health, and pose a …

A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector

JM Riveron, C Yunta, SS Ibrahim, R Djouaka, H Irving… - Genome biology, 2014 - Springer
Background Metabolic resistance to insecticides is the biggest threat to the continued
effectiveness of malaria vector control. However, its underlying molecular basis, crucial for …

Contrasting patterns of insecticide resistance and knockdown resistance (kdr) in the dengue vectors Aedes aegypti and Aedes albopictus from Malaysia

IH Ishak, Z Jaal, H Ranson, CS Wondji - Parasites & vectors, 2015 - Springer
Background Knowledge on the extent, distribution and mechanisms of insecticide resistance
is essential for successful insecticide-based dengue control interventions. Here, we report …

Mechanisms of Pyrethroid Resistance in the Dengue Mosquito Vector, Aedes aegypti: Target Site Insensitivity, Penetration, and Metabolism

S Kasai, O Komagata, K Itokawa, T Shono… - PLoS neglected …, 2014 - journals.plos.org
Aedes aegypti is the major vector of yellow and dengue fevers. After 10 generations of adult
selection, an A. aegypti strain (SP) developed 1650-fold resistance to permethrin, which is …

Cytochrome P450-based metabolic insecticide resistance in Anopheles and Aedes mosquito vectors: Muddying the waters

J Vontas, E Katsavou, K Mavridis - Pesticide biochemistry and physiology, 2020 - Elsevier
Despite the substantial progress achieved in the characterization of cytochrome P450 (CYP)-
based resistance mechanisms in mosquitoes, a number of questions remain unanswered …