Intratumoural microbiota: a new frontier in cancer development and therapy

Y Cao, H Xia, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …

Hepatocellular carcinoma mechanisms associated with chronic HCV infection and the impact of direct-acting antiviral treatment

S Dash, Y Aydin, KE Widmer… - Journal of hepatocellular …, 2020 - Taylor & Francis
Hepatitis C virus (HCV) infection is the major risk factor for liver cirrhosis and hepatocellular
carcinoma (HCC). The mechanisms of HCC initiation, growth, and metastasis appear to be …

The changing scenario of hepatocellular carcinoma in Italy: an update

F Garuti, A Neri, F Avanzato, A Gramenzi… - Liver …, 2021 - Wiley Online Library
Background and aims Epidemiology of hepatocellular carcinoma (HCC) is changing in most
areas of the world. This study aimed at updating the changing scenario of aetiology, clinical …

Risk factors and prevention of viral hepatitis-related hepatocellular carcinoma

X Zhang, L Guan, H Tian, Z Zeng, J Chen… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is a common cancer in the world, and its incidence is
increasing yearly. Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are …

Risk of hepatocellular carcinoma after HCV clearance by direct-acting antivirals treatment predictive factors and role of epigenetics

L Rinaldi, R Nevola, G Franci, A Perrella, G Corvino… - Cancers, 2020 - mdpi.com
Direct-acting antivirals (DAAs) induce a rapid virologic response (SVR) in up to 99% of
chronic hepatitis C patients. The role of SVR by DAAs on the incidence or recurrence of …

Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling

D Wang, X Zheng, B Fu, Z Nian, Y Qian, R Sun… - …, 2019 - thelancet.com
Background Patients undergoing surgical resection of hepatocellular carcinoma (HCC) are
at risk of recurrence; however, the underlying mechanism remains poorly understood …

MiR-494-3p promotes PI3K/AKT pathway hyperactivation and human hepatocellular carcinoma progression by targeting PTEN

H Lin, ZP Huang, J Liu, Y Qiu, Y Tao, M Wang, H Yao… - Scientific reports, 2018 - nature.com
Recent studies have shown that miR-494-3p is oncogene and has a central role in many
solid tumors; however, the role of miR-494-3p in the progression and prognosis of …

Chronic liver disease in humans causes expansion and differentiation of liver lymphatic endothelial cells

BAJ Tamburini, JM Finlon, AE Gillen, MS Kriss… - Frontiers in …, 2019 - frontiersin.org
Liver lymphatic vessels support liver function by draining interstitial fluid, cholesterol, fat, and
immune cells for surveillance in the liver draining lymph node. Chronic liver disease is …

[HTML][HTML] Fibrogenic signals persist in DAA-treated HCV patients after sustained virological response

C Montaldo, M Terri, V Riccioni, C Battistelli… - Journal of …, 2021 - Elsevier
Background & Aims Patients with HCV who achieve a sustained virological response (SVR)
on direct-acting antiviral (DAA) therapy still need to be monitored for signs of liver disease …

[PDF][PDF] Risk factors for the development of hepatocellular carcinoma in Chengdu: a prospective cohort study.

Q Cao, Q Zhang, YQ Chen, AD Fan… - European Review for …, 2022 - europeanreview.org
OBJECTIVE: To investigate the incidence of hepatocellular carcinoma (HCC) in Chengdu,
identify the risk factors for the development of HCC in Chengdu and provide a reference for …