Risk factors for the development of psoriasis

K Kamiya, M Kishimoto, J Sugai, M Komine… - International journal of …, 2019 - mdpi.com
Psoriasis is an immune-mediated genetic skin disease. The underlying pathomechanisms
involve complex interaction between the innate and adaptive immune system. T cells …

Psoriasis: comorbidities

F Yamazaki - The Journal of dermatology, 2021 - Wiley Online Library
Psoriasis has long been known as a disease with many complications, but was attributed to
diet and obesity. However, in recent years, psoriasis itself has been recognized as a series …

Gut–skin axis: unravelling the connection between the gut microbiome and psoriasis

AYK Thye, YR Bah, JWF Law, LTH Tan, YW He… - Biomedicines, 2022 - mdpi.com
Evidence has shown that gut microbiome plays a role in modulating the development of
diseases beyond the gastrointestinal tract, including skin disorders such as psoriasis. The …

Nutrition and psoriasis

N Kanda, T Hoashi, H Saeki - International journal of molecular sciences, 2020 - mdpi.com
Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor
necrosis factor-α/interleukin-23/interleukin-17 axis, hyperproliferation and abnormal …

Obesity-induced dysregulation of skin-resident PPARγ+ Treg cells promotes IL-17A-mediated psoriatic inflammation

P Sivasami, C Elkins, PP Diaz-Saldana, K Goss… - Immunity, 2023 - cell.com
Obesity is a major risk factor for psoriasis, but how obesity disrupts the regulatory
mechanisms that keep skin inflammation in check is unclear. Here, we found that skin was …

[HTML][HTML] Exploring the links between obesity and psoriasis: a comprehensive review

G Barros, P Duran, I Vera, V Bermúdez - International Journal of …, 2022 - mdpi.com
Obesity is a major public health issue worldwide since it is associated with the development
of chronic comorbidities such as type 2 diabetes, dyslipidemias, atherosclerosis, some …

Psoriasis and cardiovascular comorbidities: focusing on severe vascular events, cardiovascular risk factors and implications for treatment

SCS Hu, CCE Lan - International journal of molecular sciences, 2017 - mdpi.com
Psoriasis is a common and chronic inflammatory disease of the skin. It may impair the
physical and psychosocial function of patients and lead to decreased quality of life …

The Akkermansia muciniphila is a gut microbiota signature in psoriasis

LR Tan, S Zhao, W Zhu, L Wu, J Li… - Experimental …, 2018 - Wiley Online Library
Psoriasis is an immune‐mediated chronic inflammatory skin disease. Although its
pathogenesis is not fully understood, Th17 cells and the cytokines they produce, such as IL …

The gut microbiome in psoriasis and psoriatic arthritis

B Myers, N Brownstone, V Reddy, S Chan… - Best Practice & …, 2019 - Elsevier
This review summarizes existing research on the gut microbiome composition and function
in psoriasis and psoriatic arthritis, exploring potential roles in disease pathogenesis …

Cardiometabolic comorbidities in psoriasis and psoriatic arthritis

L Puig - International journal of molecular sciences, 2017 - mdpi.com
There is solid epidemiologic evidence linking psoriasis and psoriatic arthritis (PsA) to
cardiovascular risk factors and an increased risk of developing cardiovascular disease …