Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling)
information from the viscera, skin and other organs is subject to extensive processing by a …

The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

With regard to the varied, nonculinary uses of hot pepper, there is apparently little new under
the sun. For example, Incas burned dried chili peppers to combat the invading Spaniards by …

Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Background Rat oligonucleotide microarrays were used to detect changes in gene
expression in the dorsal root ganglion (DRG) 3 days following sciatic nerve transection …

The neuropeptide galanin, which is widely expressed in brain and peripheral tissues, exerts
a broad range of physiological effects. Pharmacological studies using peptide analogues …

Recent molecular cloning studies by our laboratory and others have identified the existence
of a novel rat galanin receptor subtype, GALR2. In the present study, we examined the …

The neuropeptide galanin has been implicated in the regulation of processes such as
nociception, cognition, feeding behavior, and hormone secretion. Multiple galanin receptors …

Galanin is a 29-aa neuropeptide with a complex role in pain processing. Several galanin
receptor subtypes are present in dorsal root ganglia and spinal cord with a differential …

Abstract Galanin, a 29-amino-acid peptide expressed in dorsal root ganglia (DRG) and
spinal dorsal horn interneurones, is regulated by nerve injury and peripheral inflammation …