Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications

M Nimgampalle, H Chakravarthy, S Sharma… - Ageing Research …, 2023 - Elsevier
Neurotransmitters serve as chemical messengers playing a crucial role in information
processing throughout the nervous system, and are essential for healthy physiological and …

Sex and gender differences in neurodegenerative diseases: challenges for therapeutic opportunities

A Bianco, Y Antonacci, M Liguori - International journal of molecular …, 2023 - mdpi.com
The term “neurodegenerative diseases”(NDs) identifies a group of heterogeneous diseases
characterized by progressive loss of selectively vulnerable populations of neurons, which …

[HTML][HTML] Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system

V Fominykh, AA Shadrin, PP Jaholkowski… - Neurobiology of …, 2023 - Elsevier
Background Neuroinflammation is involved in the pathophysiology of Alzheimer's disease
(AD), including immune-linked genetic variants and molecular pathways, microglia and …

Dissecting the relationship between neuropsychiatric and neurodegenerative disorders

R Gupta, D Advani, D Yadav, RK Ambasta… - Molecular …, 2023 - Springer
Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

Disease-modifying therapies used to treat multiple sclerosis and the gut microbiome: a systematic review

CC Tsai, S Jette, H Tremlett - Journal of Neurology, 2024 - Springer
Background The gut microbiome may play a role in multiple sclerosis (MS). However, its
relationship with the disease-modifying therapies (DMTs) remains unclear. We …

Highly effective therapy versus escalation approaches in early multiple sclerosis: what is the future of multiple sclerosis treatment?

NB Rjeily, EM Mowry, D Ontaneda… - Neurologic …, 2024 - neurologic.theclinics.com
Multiple sclerosis (MS) is a chronic disease of the central nervous system with a global
prevalence of more than 2 million cases worldwide 1 and nearly one million cases in the US …

ROS-Scavenging Lignin-Based Tolerogenic Nanoparticle Vaccine for Treatment of Multiple Sclerosis

NM Phan, TL Nguyen, H Shin, TA Trinh, J Kim - ACS nano, 2023 - ACS Publications
Multiple sclerosis (MS) is a demyelinating autoimmune disease, in which the immune
system attacks myelin. Although systemic immunosuppressive agents have been used to …

Surprising magic of CD24 beyond cancer

H Wang, P Shi, X Shi, Y Lv, H Xie, H Zhao - Frontiers in Immunology, 2024 - frontiersin.org
CD24 has emerged as a molecule of significant interest beyond the oncological arena.
Recent studies have unveiled its surprising and diverse roles in various biological …

Immune System Dysregulation in the Progression of Multiple Sclerosis: Molecular Insights and Therapeutic Implications

Z Khan, S Mehan, GD Gupta, AS Narula - Neuroscience, 2024 - Elsevier
Multiple sclerosis (MS), a prevalent neurological disorder, predominantly affects young
adults and is characterized by chronic autoimmune activity. The study explores the immune …

The neuroprotective potential of mesenchymal stem cells from bone marrow and human exfoliated deciduous teeth in a murine model of demyelination

T Kråkenes, S Wergeland, N Al-Sharabi… - Plos one, 2023 - journals.plos.org
Introduction Multiple sclerosis (MS) is characterized by chronic inflammation, demyelination,
and axonal degeneration within the central nervous system (CNS), for which there is no …