Diagnosis and treatment of non-muscle invasive bladder cancer: AUA/SUO guideline

SS Chang, SA Boorjian, R Chou, PE Clark… - The Journal of …, 2016 - auajournals.org
Purpose: Although associated with an overall favorable survival rate, the heterogeneity of
non-muscle invasive bladder cancer (NMIBC) affects patients' rates of recurrence and …

Definitions, end points, and clinical trial designs for non–muscle-invasive bladder cancer: recommendations from the International Bladder Cancer Group

AM Kamat, RJ Sylvester, A Böhle, J Palou… - Journal of Clinical …, 2016 - ascopubs.org
Purpose To provide recommendations on appropriate clinical trial designs in non–muscle-
invasive bladder cancer (NMIBC) based on current literature and expert consensus of the …

Pembrolizumab monotherapy for the treatment of high-risk non-muscle-invasive bladder cancer unresponsive to BCG (KEYNOTE-057): an open-label, single-arm …

AV Balar, AM Kamat, GS Kulkarni, EM Uchio… - The Lancet …, 2021 - thelancet.com
Background Standard treatment for high-risk non-muscle-invasive bladder cancer is
transurethral resection of bladder tumour followed by intravesical BCG immunotherapy …

Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial

SA Boorjian, M Alemozaffar, BR Konety… - The Lancet …, 2021 - thelancet.com
Background BCG is the most effective therapy for high-risk non-muscle-invasive bladder
cancer. Nadofaragene firadenovec (also known as rAd-IFNa/Syn3) is a replication-deficient …

Multi-institution evaluation of sequential gemcitabine and docetaxel as rescue therapy for nonmuscle invasive bladder cancer

RL Steinberg, LJ Thomas, N Brooks, SL Mott… - The Journal of …, 2020 - auajournals.org
Purpose: Rescue intravesical therapies for patients with bacillus Calmette-Guérin failure
nonmuscle invasive bladder cancer remain a critical focus of ongoing research. Sequential …

IL-15 superagonist NAI in BCG-unresponsive non–muscle-invasive bladder cancer

K Chamie, SS Chang, E Kramolowsky… - NEJM …, 2022 - evidence.nejm.org
Abstract Background Patients with Bacillus Calmette–Guérin (BCG)–unresponsive non–
muscle-invasive bladder cancer (NMIBC) have limited treatment options. The immune cell …

Phase 2 trial of atezolizumab in bacillus Calmette-Guérin–unresponsive high-risk non–muscle-invasive bladder cancer: SWOG S1605

PC Black, CM Tangen, P Singh, DJ McConkey… - European urology, 2023 - Elsevier
Background Although radical cystectomy (RC) is the standard of care for patients with
bacillus Calmette-Guérin (BCG)-unresponsive high-risk non–muscle-invasive bladder …

Intravesical rAd–IFNα/Syn3 for patients with high-grade, Bacillus Calmette-Guerin–refractory or relapsed non–muscle-invasive bladder cancer: a phase II randomized …

ND Shore, SA Boorjian, DJ Canter, K Ogan… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Many patients with high-risk non–muscle-invasive bladder cancer (NMIBC) are
either refractory to bacillus Calmette-Guerin (BCG) treatment or may experience disease …

International Bladder Cancer Group consensus statement on clinical trial design for patients with bacillus Calmette-Guérin–exposed high-risk non–muscle-invasive …

M Roumiguié, AM Kamat, TJ Bivalacqua, SP Lerner… - European urology, 2022 - Elsevier
Context A large proportion of patients with non–muscle-invasive bladder cancer (NMIBC) fall
in the gap between bacillus Calmette-Guérin (BCG)-naïve and BCG-unresponsive disease …

Radiofrequency-induced thermo-chemotherapy effect versus a second course of bacillus Calmette-Guérin or institutional standard in patients with recurrence of non …

WS Tan, A Panchal, L Buckley, AJ Devall, LS Loubière… - European urology, 2019 - Elsevier
Background There is no effective intravesical second-line therapy for non–muscle-invasive
bladder cancer (NMIBC) when bacillus Calmette-Guérin (BCG) fails. Objective To compare …