Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
COVID-19 vaccines: rapid development, implications, challenges and future prospects
S Kashte, A Gulbake, SF El-Amin III, A Gupta - Human cell, 2021 - Springer
COVID-19 has affected millions of people and put an unparalleled burden on healthcare
systems as well as economies throughout the world. Currently, there is no decisive therapy …
systems as well as economies throughout the world. Currently, there is no decisive therapy …
[HTML][HTML] T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
Coronavirus Disease 2019 (COVID-19), has caused a global pandemic, and safe, effective …
Coronavirus Disease 2019 (COVID-19), has caused a global pandemic, and safe, effective …
Sputnik V COVID-19 vaccine candidate appears safe and effective
I Jones, P Roy - The Lancet, 2021 - thelancet.com
Denis Logunov and colleagues1 report their interim results from a phase 3 trial of the
Sputnik V COVID-19 vaccine in The Lancet. The trial results show a consistent strong …
Sputnik V COVID-19 vaccine in The Lancet. The trial results show a consistent strong …
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
More than 190 vaccines are currently in development to prevent infection by the novel
severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while …
severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while …
Efficacy and safety of COVID-19 vaccines in older people
RL Soiza, C Scicluna, EC Thomson - Age and ageing, 2021 - academic.oup.com
Several vaccines against coronavirus disease 2019 (COVID-19) are on the cusp of
regulatory approval. Their safety and efficacy in older people is critical to their success. Even …
regulatory approval. Their safety and efficacy in older people is critical to their success. Even …
Adverse events reported from COVID-19 vaccine trials: a systematic review
RJ Kaur, S Dutta, P Bhardwaj, J Charan… - Indian Journal of Clinical …, 2021 - Springer
COVID-19 infection originated in Wuhan, China in December 2019 and crippled human
health globally in no time. The public health emergency required urgent efforts to develop …
health globally in no time. The public health emergency required urgent efforts to develop …
Quantification of SARS-CoV-2 neutralizing antibody by wild-type plaque reduction neutralization, microneutralization and pseudotyped virus neutralization assays
KR Bewley, NS Coombes, L Gagnon, L McInroy… - Nature protocols, 2021 - nature.com
Virus neutralization assays measure neutralizing antibodies in serum and plasma, and the
plaque reduction neutralization test (PRNT) is considered the gold standard for measuring …
plaque reduction neutralization test (PRNT) is considered the gold standard for measuring …
COVID-19: coronavirus vaccine development updates
J Zhao, S Zhao, J Ou, J Zhang, W Lan, W Guan… - Frontiers in …, 2020 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2), a newly emerged coronavirus, and has been pandemic since …
Coronavirus 2 (SARS-CoV-2), a newly emerged coronavirus, and has been pandemic since …
[HTML][HTML] Novel approaches for vaccine development
MS Gebre, LA Brito, LH Tostanoski, DK Edwards… - Cell, 2021 - cell.com
Vaccines are critical tools for maintaining global health. Traditional vaccine technologies
have been used across a wide range of bacterial and viral pathogens, yet there are a …
have been used across a wide range of bacterial and viral pathogens, yet there are a …