Treatment of cryptococcal meningitis: how have we got here and where are we going?

NTT Ngan, B Flower, JN Day - Drugs, 2022 - Springer
Cryptococcal meningitis is a devastating brain infection cause by encapsulated yeasts of the
Cryptococcus genus. Exposure, through inhalation, is likely universal by adulthood, but …

Meningitis in adults: diagnosis and management

N Young, M Thomas - Internal medicine journal, 2018 - Wiley Online Library
Bacterial meningitis is a medical emergency. All clinicians who provide acute medical care
require a sound understanding of the priorities of managing a patient with suspected …

Cerebrospinal fluid analysis

B Shahan, EY Choi, G Nieves - American Family Physician, 2021 - aafp.org
Cerebrospinal fluid (CSF) analysis is a diagnostic tool for many conditions affecting the
central nervous system. Urgent indications for lumbar puncture include suspected central …

New insights into HIV/AIDS‐associated cryptococcosis

S Antinori - International Scholarly Research Notices, 2013 - Wiley Online Library
Cryptococcal meningitis is a life‐threatening opportunistic fungal infection in both HIV‐
infected and HIV‐uninfected patients. According to the most recent taxonomy, the …

Cryptococcal neuroradiological lesions correlate with severity during cryptococcal meningoencephalitis in HIV-positive patients in the HAART era

C Charlier, F Dromer, C Leveque, L Chartier… - PloS one, 2008 - journals.plos.org
Cryptococcal meningoencephalitis has an overall global mortality rate of 20% in AIDS
patients despite antifungals. There is a need for additional means of precise assessment of …

Neurologic diseases in HIV-infected patients

M Bilgrami, P O'keefe - Handbook of clinical neurology, 2014 - Elsevier
Since the introduction of highly active antiretroviral therapy there has been an improvement
in the quality of life for people with HIV infection. Despite the progress made, about 70% of …

Cryptococcal meningitis in human immunodeficiency virus-infected patients in Harare, Zimbabwe

RS Heyderman, IT Gangaidzo, JG Hakim… - Clinical infectious …, 1998 - academic.oup.com
A prospective observational study was conducted over a 10-month period to determine the
clinical and laboratory manifestations of cryptococcal meningitis in Zimbabwe, a country …

Cryptococcal immune reconstitution inflammatory syndrome: report of four cases in three patients and review of the literature

DJ Skiest, LJ Hester, RD Hardy - Journal of Infection, 2005 - Elsevier
Immune reconstitution inflammatory syndromes (IRIS) in patients with AIDS are
characterized by atypical manifestations of opportunistic pathogens in patients experiencing …

A novel method for identifying and distinguishing Cryptococcus neoformans and Cryptococcus gattii by surface-enhanced Raman scattering using positively charged …

S Hu, F Gu, M Chen, C Wang, J Li, J Yang, G Wang… - Scientific Reports, 2020 - nature.com
There are approximately 1 million cryptococcal infections per year among HIV+ individuals,
resulting in nearly 625,000 deaths. Cryptococcus neoformans and Cryptococcus gattii are …

Disseminated cryptococcosis with brain involvement in patients with chronic lymphoid malignancies on ibrutinib

JA Messina, EK Maziarz, A Spec… - Open forum …, 2017 - academic.oup.com
We report 2 cases of disseminated cryptococcosis with central nervous system involvement
in patients with chronic lymphoid malignancies occurring within 1 month of starting on …