Chiral recognition and determination of enantiomeric excess by mass spectrometry: A review

X Yu, ZP Yao - Analytica chimica acta, 2017 - Elsevier
Chiral analysis is of great importance to fundamental and applied research in chemical,
biological and pharmaceutical sciences. Due to the superiority of mass spectrometry (MS) …

Chiral mass spectrometry: An overview

DQ Han, ZP Yao - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Chiral analysis by mass spectrometry has attracted much attention due to its advantages in
speed, sensitivity and specificity. In this review, recent advances in chiral analysis by mass …

Copper(II)-Assisted Enantiomeric Analysis of d,l-Amino Acids Using the Kinetic Method:  Chiral Recognition and Quantification in the Gas Phase

WA Tao, D Zhang, EN Nikolaev… - Journal of the American …, 2000 - ACS Publications
Chiral recognition of d-and l-amino acids is achieved and mixtures of enantiomers quantified
in the gas phase, using the kinetics of competitive unimolecular fragmentations of trimeric …

The kinetic method of making thermochemical determinations

RG Cooks, JT Koskinen… - Journal of mass …, 1999 - Wiley Online Library
This critical examination of the kinetic method is carried out as part of a dialog‐in‐print with
Peter Armentrout and László Drahos and Károly Vékey. We summarise the characteristics of …

Mass spectrometric quantitation of chiral drugs by the kinetic method

WA Tao, FC Gozzo, RG Cooks - Analytical chemistry, 2001 - ACS Publications
A novel mass spectrometric method for rapid, accurate (2− 4% ee) quantitation of chiral
drugs is described. Copper (II)-bound complexes of seven model drugs (atenolol, DOPA …

Energy‐dependent dissociation of benzylpyridinium ions in an ion‐trap mass spectrometer

EL Zins, C Pepe, D Schröder - Journal of mass spectrometry, 2010 - Wiley Online Library
Benzylpyridinium ions, generated via electrospray ionization of dilute solutions of their salts
in acetonitrile/water, are probed by collisional activation in an ion‐trap mass spectrometer …

Multidimensional analysis of 16 glucose isomers by ion mobility spectrometry

MM Gaye, G Nagy, DE Clemmer, NLB Pohl - Analytical chemistry, 2016 - ACS Publications
Diastereomeric adducts comprising an enantiomerically pure monosaccharide analyte, a
peptide, and/or an amino acid and a divalent metal ion (for 16 different monosaccharide …

Kinetic Resolution of d,l-Amino Acids Based on Gas-Phase Dissociation of Copper(II) Complexes

WA Tao, D Zhang, F Wang, PD Thomas… - Analytical …, 1999 - ACS Publications
Chiral recognition of d-and l-amino acids is achieved in the gas phase on the basis of the
kinetics of competitive fragmentations of trimeric Cu (II)-bound complexes. The singly …

Enantioselectivity of mass spectrometry: challenges and promises

H Awad, A El‐Aneed - Mass Spectrometry Reviews, 2013 - Wiley Online Library
With the fast growing market of pure enantiomer drugs and bioactive molecules, new chiral‐
selective analytical tools have been instigated including the use of mass spectrometry (MS) …

Chiral analysis by electrospray ionization mass spectrometry/mass spectrometry. 1. Chiral recognition of 19 common amino acids

ZP Yao, TSM Wan, KP Kwong, CT Che - Analytical chemistry, 2000 - ACS Publications
Chiral recognition of 19 common amino acids was achieved by investigating the collision-
induced dissociation spectra of protonated trimers that were formed from the electrospray …