The cytokine, TNF, participates in virtually every aspect of stroke. Its effects, however, often
appear contradictory. Analysis of the current model for TNF receptor signaling and TNF …

Synovial inflammation in rheumatoid arthritis is closely related to the formation of ectopic
lymphoid microstructures. In synovial tissue from some patients, one finds seemingly diffuse …

Background—Rheumatoid arthritis may be associated with an increased risk of
cardiovascular disease. We compared the incidence rates of myocardial infarction and …

Loneliness can be defined as perceived social isolation and appears to be a relatively
common experience in adults. It carries a significant health risk and has been associated …

Background—CD4 T lymphocytes accumulate in unstable plaque. The direct and indirect
involvement of these T cells in tissue injury and plaque instability is not understood. Methods …

Objective The risk of cardiovascular disease (CVD) is increased in patients with rheumatoid
arthritis (RA). The objective of this study was to examine the distribution of known CVD risk …

Psoriasis has been traditionally viewed as an inflammatory skin disorder of unknown origin.
Recent advances in the immunopathogenesis and genetics of psoriasis have broadened …

Background The relationship between psoriasis and associated diseases has drawn
particular interest in recent years. To provide appropriate management of psoriasis from an …

Rheumatoid arthritis (RA), like many other autoimmune syndromes, is a disease of adults,
with the highest incidence rates reported in the elderly. The immune system undergoes …

The risk for cardiovascular (CV) disease is increased in rheumatoid arthritis (RA) but data on
the burden of coronary atherosclerosis in patients with RA are lacking. We conducted a …