The risk for cardiovascular (CV) disease is increased in rheumatoid arthritis (RA) but data on
the burden of coronary atherosclerosis in patients with RA are lacking. We conducted a …

Acute coronary syndromes (ACS) are precipitated by a rupture of the atherosclerotic plaque,
often at the site of T cell and macrophage infiltration. Here, we show that plaque-infiltrating …

During recent years, the ubiquitin–proteasome system has become known as the major
pathway of non-lysosomal degradation of intracellular proteins, involving two sequential …

Current disease models of autoimmune syndromes, such as rheumatoid arthritis, propose
that chronic inflammation is caused by 'forbidden T-cell clones' that recognize disease …

Aims HMG-CoA reductase inhibitors (statins) reduce cardiovascular mortality and morbidity
in patients with stable coronary artery disease as well as acute coronary syndrome (ACS). It …

Obstructive sleep apnea (OSA), a breathing disorder in sleep characterized by intermittent
hypoxia and sleep fragmentation, constitutes an independent risk factor for cardiovascular …

Published data and independent author's information related with the mechanisms of
development of atherosclerotic vascular lesions in inflammatory rheumatic diseases are …

The relationship between psoriasis and associated diseases has drawn particular interest in
recent years. To provide appropriate management of psoriasis from an early stage, it is …

Newly identified T helper cell 22 (Th22) is a subset of CD4+ T cells with specific properties
apart from other known CD4+ T cell subsets. Th22 is obviously discrete from Th17 and Th1 …

The inflammatory infiltrate in atherosclerotic plaque is composed of T cells and
macrophages. CD4+ T cells with a unique phenotype, CD4+ CD28null, are preferentially …