Obesity and hidradenitis suppurativa: targeting meta-inflammation for therapeutic gain
D Mintoff, R Agius, F Benhadou, A Das… - Clinical and …, 2023 - academic.oup.com
Hidradenitis suppurativa (HS) is a chronic, inflammatory condition of the pilosebaceous unit.
The typical patient with HS is characterized as someone with obesity, who smokes and who …
The typical patient with HS is characterized as someone with obesity, who smokes and who …
Secukinumab in the treatment of hidradenitis suppurativa
CL Snyder, RS Gibson, ML Porter, AB Kimball - Immunotherapy, 2023 - Taylor & Francis
The IL-17 pathways are involved in the pathophysiology of many inflammatory skin
conditions, including hidradenitis suppurativa. Secukinumab, an IL-17A inhibitor, has been …
conditions, including hidradenitis suppurativa. Secukinumab, an IL-17A inhibitor, has been …
Hidradenitis suppurativa presents a methylome dysregulation capable to explain the pro‐inflammatory microenvironment: Are these DNA methylations potential …
U Radhakrishna, U Ratnamala… - Journal of the …, 2023 - Wiley Online Library
Background Hidradenitis suppurativa (HS) is a chronic, systemic, inflammatory skin
condition with elusive pathogenesis that affects therapeutic intervention directly. Objective …
condition with elusive pathogenesis that affects therapeutic intervention directly. Objective …
Hidradenitis suppurativa associated telomere‐methylome dysregulations in blood
U Radhakrishna, U Ratnamala… - Journal of the …, 2024 - Wiley Online Library
Background Hidradenitis suppurativa (HS) is a chronic debilitating disease with a significant
burden of both organic and psychological comorbidities. It has been shown that certain …
burden of both organic and psychological comorbidities. It has been shown that certain …
DNA methylation profiling and integrative multi-omics analysis of skin samples reveal important contribution of epigenetics and immune response in the pathogenesis …
L Liu, Y Xue, J Chen, Y Li, T Chen, X Pan, J Zhong… - Clinical …, 2023 - Elsevier
The regulatory effect of DNA methylation on the pathogenesis of acne vulgaris is completely
unknown. Herein we analyzed the DNA methylation profile in skin samples of acne vulgaris …
unknown. Herein we analyzed the DNA methylation profile in skin samples of acne vulgaris …
[HTML][HTML] Comparative diet-gut microbiome analysis in Crohn's disease and Hidradenitis suppurativa
Introduction The chronic inflammatory skin disease Hidradenitis suppurativa (HS) is strongly
associated with Crohn's Disease (CD). HS and CD share clinical similarities and similar …
associated with Crohn's Disease (CD). HS and CD share clinical similarities and similar …
Cytochrome P450 genes mediated by DNA methylation are involved in the resistance to hidradenitis suppurativa
U Radhakrishna, U Ratnamala… - The Journal of …, 2023 - pubmed.ncbi.nlm.nih.gov
Cytochrome P450 Genes Mediated by DNA Methylation Are Involved in the Resistance to
Hidradenitis Suppurativa Cytochrome P450 Genes Mediated by DNA Methylation Are …
Hidradenitis Suppurativa Cytochrome P450 Genes Mediated by DNA Methylation Are …
Hidradenitis suppurativa in Black and White patients-a clinical study
AS Byrd, AZ Rosenberg, WD Shipman… - European review for …, 2023 - air.unimi.it
OBJECTIVE: It is suggested that hidradenitis suppurativa (HS) is more prevalent and causes
greater morbidity in Black patients than in White. Clinical data are however lacking …
greater morbidity in Black patients than in White. Clinical data are however lacking …
[HTML][HTML] An Updated Mutation Spectrum of the γ-Secretase Complex: Novel NCSTN Gene Mutation in an Indian Family with Hidradenitis Suppurativa and Acne …
Background: Hidradenitis suppurativa (HS) is a complex, chronic inflammatory skin disorder
whose pathophysiology is poorly understood. Genetic studies have shown that HS is …
whose pathophysiology is poorly understood. Genetic studies have shown that HS is …
Biosensing circulating MicroRNAs in autoinflammatory skin diseases: Focus on Hidradenitis suppurativa
MicroRNAs (miRNAs) play a crucial role in the early diagnosis of autoinflammatory
diseases, with Hidradenitis Suppurativa (HS) being a notable example. HS, an …
diseases, with Hidradenitis Suppurativa (HS) being a notable example. HS, an …