Bacterial infections represent a significant health threat globally, and are responsible for the
majority of hospital-acquired infections, leading to extensive mortality and burden on global …

Bacteria secrete small molecules known as siderophores to acquire iron from their
surroundings. For over 60 years, investigations into the bioinorganic chemistry of these …

The global crisis of untreatable microbial infections necessitates the design of new
antibiotics. Drug repurposing is a promising strategy for expanding the antibiotic repertoire …

The “phenylpropenoids” are a well-known set of naturally occurring compounds obtained
mainly from plant sources. 1, 2 Of this group, the generalized 2-propenylbenzenes 1 and 1 …

The rapid emergence of antimicrobial resistance (AMR) pathogens highlights the urgent
need to approach this global burden with alternative strategies. Cefiderocol (Fetroja®) is a …

The accelerated appearance of drug-resistant bacteria poses an ever-growing threat to
modern medicine's capacity to fight infectious diseases. Gram-positive species such as …

Elucidating the benefits of individual microbiota-derived molecules in host animals is
important for understanding the symbiosis between humans and their microbiota. The …

Antimicrobial resistance (AMR) is a global threat to society due to the increasing emergence
of multi-drug resistant bacteria that are not susceptible to our last line of defence antibiotics …

Covering: up to the end of 2016 Novel antimicrobial drugs are continuously needed to
counteract bacterial resistance development. An innovative molecular design strategy for …

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for
nosocomial infections. The prevalence of antibiotic-resistant P. aeruginosa strains is …