Human milk oligosaccharides: potential therapeutic aids for allergic diseases

I Tarrant, BB Finlay - Trends in Immunology, 2023 - cell.com
Human milk oligosaccharides: potential therapeutic aids for allergic diseases: Trends in
Immunology Skip to Main Content Advertisement Trends in Immunology This journal offers …

Immunomodulatory properties of mesenchymal stem cells: A potential therapeutic strategy for allergic rhinitis

M Wang, N Zhao, C Wang, ZB Jin, L Zhang - Allergy, 2023 - Wiley Online Library
Allergic rhinitis is a highly prevalent chronic inflammatory disorder of the nasal mucosa that
poses a significant burden on patients' health and quality of life. Current therapies for …

Use of a liver-targeting immune-tolerogenic mRNA lipid nanoparticle platform to treat peanut-induced anaphylaxis by single-and multiple-epitope nucleotide …

X Xu, X Wang, YP Liao, L Luo, T Xia, AE Nel - ACS nano, 2023 - ACS Publications
While oral desensitization is capable of alleviating peanut allergen anaphylaxis, long-term
immune tolerance is the sought-after goal. We developed a liver-targeting lipid nanoparticle …

[HTML][HTML] Allergoid–mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring

C Benito-Villalvilla, M Pérez-Diego, A Angelina… - Journal of Allergy and …, 2022 - Elsevier
Background Allergoid–mannan conjugates are novel vaccines for allergen-specific
immunotherapy being currently assayed in phase 2 clinical trials. Allergoid–mannan …

[HTML][HTML] Therapeutic potency of curcumin for allergic diseases: A focus on immunomodulatory actions

SM Haftcheshmeh, SR Mirhafez, M Abedi… - Biomedicine & …, 2022 - Elsevier
In light of increasing research evidence on the molecular mechanisms of allergic diseases,
the crucial roles of innate and acquired immunity in the disease's pathogenesis have been …

Vitamin D3 priming of dendritic cells shifts human neutrophil-dependent Th17 cell development to regulatory T cells

FMJ Hafkamp, EWM Taanman-Kueter… - Frontiers in …, 2022 - frontiersin.org
Vitamin D3 (VD3) is a potential adjuvant for use in tolerogenic vaccine formulations that
target dendritic cells (DCs) for the treatment of chronic inflammatory disorders, eg …

[HTML][HTML] Regulatory T cells, a viable target against airway allergic inflammatory responses in asthma

J Zhang, Y Zou, L Chen, Q Xu, Y Wang, M Xie… - Frontiers in …, 2022 - frontiersin.org
Asthma is a multifactorial disorder characterized by the airway chronic inflammation, hyper-
responsiveness (AHR), remodeling, and reversible obstruction. Although asthma is known …

[HTML][HTML] Treg-targeted efficient-inducible platform for collagen-induced arthritis treatment

L Wang, Y Wang, C Liu, J He, X He, X Zhang, C Zhu… - Materials Today Bio, 2023 - Elsevier
Regulatory T cells (Tregs) display great promise in rheumatoid arthritis (RA) therapy.
However, their low number and differentiation rate limit their further application in the clinics …

[HTML][HTML] Functional diversities of regulatory T cells in the context of cancer immunotherapy

R Gao, GP Shi, J Wang - Frontiers in Immunology, 2022 - frontiersin.org
Regulatory T cells (Tregs) are a subset of CD4+ T cells with their immunosuppressive
activities to block abnormal or excessive immune responses to self and non-autoantigens …

New insights into the role of PD-1 and its ligands in allergic disease

MA Galván Morales, JM Montero-Vargas… - International Journal of …, 2021 - mdpi.com
Programmed cell death 1 (PD-1) and its ligands PD-L1 and PD-L2 are receptors that act in
co-stimulatory and coinhibitory immune responses. Signaling the PD-1/PD-L1 or PD-L2 …