From cells to organoids: The evolution of blood-brain barrier technology for modelling drug delivery in brain cancer

E Gonzales-Aloy, A Ahmed-Cox, M Tsoli… - Advanced Drug Delivery …, 2023 - Elsevier
Brain cancer remains the deadliest cancer. The blood–brain barrier (BBB) is impenetrable to
most drugs and is a complex 3D network of multiple cell types including endothelial cells …

Functionalized magnetic nanoparticles for alternating magnetic field-or near infrared light-induced cancer therapies

AT Shivanna, BS Dash, JP Chen - Micromachines, 2022 - mdpi.com
The multi-faceted nature of functionalized magnetic nanoparticles (fMNPs) is well-suited for
cancer therapy. These nanocomposites can also provide a multimodal platform for targeted …

Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM

B Liu, Q Ji, Y Cheng, M Liu, B Zhang, Q Mei… - Journal of …, 2022 - Springer
Background Clinical studies have shown that the efficacy of programmed cell death receptor-
1/programmed cell death ligand-1 (PD-1/PD-L1) inhibitors on glioblastoma (GBM) is much …

Superparamagnetic iron oxide nanoparticles for immunotherapy of cancers through macrophages and magnetic hyperthermia

AMM Dias, A Courteau, PS Bellaye, E Kohli, A Oudot… - Pharmaceutics, 2022 - mdpi.com
Cancer immunotherapy has tremendous promise, but it has yet to be clinically applied in a
wider variety of tumor situations. Many therapeutic combinations are envisaged to improve …

Recent trends in biologically synthesized metal nanoparticles and their biomedical applications: a review

L Devi, P Kushwaha, TM Ansari, A Kumar… - Biological Trace Element …, 2024 - Springer
In recent years, biologically synthesized metal nanoparticles have emerged as a dynamic
field of research with significant implications for biomedical applications. This review …

Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy

S Kumar, MK Shukla, AK Sharma, GK Jayaprakash… - MedComm, 2023 - Wiley Online Library
Cancer is a disease associated with complex pathology and one of the most prevalent and
leading reasons for mortality in the world. Current chemotherapy has challenges with …

Understanding MNPs behaviour in response to AMF in biological milieus and the effects at the cellular level: Implications for a rational design that drives magnetic …

D Egea-Benavente, JG Ovejero, MP Morales… - Cancers, 2021 - mdpi.com
Simple Summary Magnetic hyperthermia therapy is an alternative treatment for cancer that
complements traditional therapies and that has shown great promise in recent years. In this …

Applications of iron oxide nanoparticles against breast cancer

H Hosseinkazemi, S Samani, A O'Neill… - Journal of …, 2022 - Wiley Online Library
Breast cancer is the most common cancer diagnosed in women, with an estimated 12% of
women in the United States affected during their lifetime. Researchers have demonstrated …

Light-Driven and Metal–Organic Framework Synergetic Loaded DNA Tetrahedral Amplifier for Exonuclease III-Powered All-in-One Biosensing and Chemotherapy in …

YL Chen, X Sun, JW He, MK Xin, D Liu… - ACS Applied Materials & …, 2023 - ACS Publications
As a result of inaccurate biosensing and difficult synergetic loading, it is challenging to
further impel DNA amplifiers to perform therapeutic application. Herein, we introduce some …

Smart and multi-functional magnetic nanoparticles for cancer treatment applications: clinical challenges and future prospects

E Aram, M Moeni, R Abedizadeh, D Sabour… - Nanomaterials, 2022 - mdpi.com
Iron oxide nanoparticle (IONPs) have become a subject of interest in various biomedical
fields due to their magnetism and biocompatibility. They can be utilized as heat mediators in …