Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function

E Dale, AL Pehrson, T Jeyarajah, Y Li, SC Leiser… - CNS …, 2016 - cambridge.org
The hippocampus plays an important role in emotional and cognitive processing, and both
of these domains are affected in patients with major depressive disorder (MDD). Extensive …

The catecholaminergic–cholinergic balance hypothesis of bipolar disorder revisited

J van Enkhuizen, DS Janowsky, B Olivier… - European journal of …, 2015 - Elsevier
Bipolar disorder is a unique illness characterized by fluctuations between mood states of
depression and mania. Originally, an adrenergic–cholinergic balance hypothesis was …

Long-Term exposure to SSRI citalopram induces neurotoxic effects in zebrafish

X Hong, R Chen, L Zhang, L Yan, J Xin… - … Science & Technology, 2022 - ACS Publications
Residual antidepressants are of increasing concern worldwide, yet critical information on
their long-term neurotoxic impacts on nontarget aquatic animals is lacking. Here, we …

The cholinergic system and depression

G Dagytė, JA Den Boer, A Trentani - Behavioural brain research, 2011 - Elsevier
Major depressive disorder is a severe psychiatric condition which forms a substantial burden
to patients and society. Despite continuous efforts to unravel its etiology and …

[HTML][HTML] Fluoxetine reverses depressive-like behaviors and increases hippocampal acetylcholinesterase activity induced by olfactory bulbectomy

DG Machado, MP Cunha, VB Neis, GO Balen… - Pharmacology …, 2012 - Elsevier
The olfactory bulbectomy (OB) is an animal model of depression that results in behavioral,
neurochemical and neuroendocrinological changes, features comparable to those seen in …

[HTML][HTML] Reversal of age-associated cognitive deficits is accompanied by increased plasticity-related gene expression after chronic antidepressant administration in …

Y Li, A Abdourahman, JA Tamm, AL Pehrson… - Pharmacology …, 2015 - Elsevier
Cognitive decline occurs during healthy aging, even in middle-aged subjects, via
mechanisms that could include reduced stem cell proliferation, changed growth factor …

Recent advances in Cannabis sativa research: biosynthetic studies and its potential in biotechnology

S Sirikantaramas, F Taura, S Morimoto… - Current …, 2007 - ingentaconnect.com
Cannabinoids, consiting of alkylresorcinol and monoterpene groups, are the unique
secondary metabolites that are found only in Cannabis sativa. Tetrahydrocannabinol (THC) …

[图书][B] Ur balans: om stress, utbrändhet och vägar tillbaka till ett balanserat liv

A Perski - 2015 - books.google.com
En dag hittas Barbro, 35, död på köksgolvet med pennan kvar i handen. Dödorsak: stress.
Ur balans tar ett vidare grepp på stress i vår vardag–missbruket av vår tid och den livsfarliga …

[HTML][HTML] Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3β …

YJ Wang, QG Ren, WG Gong, D Wu, X Tang, XL Li… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Tau hyperphosphorylation is an important pathological feature of Alzheimer's disease (AD).
To investigate whether escitalopram could inhibit amyloid-β (Aβ)-induced tau …

Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice

AV Kalueff, CL Jensen, DL Murphy - Brain research, 2007 - Elsevier
Serotonin transporter knockout (SERT−/−) mice are extensively used as a genetic model of
several neuropsychiatric disorders, and consistently display anxiety-like behaviors and …