The harmful use of alcohol is a worldwide problem. It has been estimated that alcohol abuse
represents the world's third largest risk factor for disease and disability; it is a causal factor of …

The aim of evidence-based medicine is to improve the quality of health care by integrating
the best research evidence with clinical expertise and patient values. Evidence-based …

RH: consultant to Takeda R&D Europe and have been a speaker for Takeda symposia also
a consultant to Novartis and Insys. DA: consulted with Pfizer on PPI therapy, after completion …

Background & Aims The prevalence and risk factors of Barrett's esophagus (BE) in Asian
countries are unclear. Studies report a wide range of BE prevalence in Asian countries. We …

Gastroesophageal reflux impairs the mucosal barrier in the distal esophagus, allowing
chronic exposure of the squamous epithelium to multitudinous stimulations and inducing …

Background Central obesity has been suggested as a risk factor for gastroesophageal reflux
disease. The aim of this study was to evaluate the association of visceral fat area and other …

Background: Barrett's esophagus (BE) is a precursor lesion of esophageal adenocarcinoma.
Besides gastroesophageal reflux, possible risk factors for BE include overweight, cigarette …

Alcohol consumption affects gastric mucosa by multiple and complex mechanisms
depending either by direct contact of ethanol or by indirect biological damage induced by its …

Esophageal cancer is the eighth most common type of cancer in the world, and the sixth
most common cause of mortality from cancer. Alcohol consumption is the major risk factor for …

Aims: Dietary habits are reported to be associated with Barrett's esophagus (BE) risk;
however, whether there is a causal relationship remains controversial. Here, we …