Method for producing and cleaving a fusion proteins with an n-terminal chymosin pro-peptide
M Moloney, J Alcantara, G Van Rooijen - US Patent 7,501,265, 2009 - Google Patents
An improved method for recovering recombinantly produced polypeptides is described. The
method involves expressing the recombinant polypeptide as a fusion protein with a pro …
method involves expressing the recombinant polypeptide as a fusion protein with a pro …
Humanized light chain mice
L MacDonald, C Gurer, KA Hosiawa… - US Patent …, 2020 - Google Patents
2017-08-01 Assigned to REGENERON PHARMACEUTICALS, INC. reassignment
REGENERON PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
REGENERON PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
J Clube - US Patent 11,297,811, 2022 - Google Patents
The present invention relates to humanisation of antibodies in vivo. The invention provides
non-human vertebrates, cells, populations and methods useful for humanising chi maeric …
non-human vertebrates, cells, populations and methods useful for humanising chi maeric …
FK506-based regulation of biological events
PA Clemons, BG Gladstone, A Seth… - US Patent …, 2006 - Google Patents
US7109317B1 - FK506-based regulation of biological events - Google Patents US7109317B1
- FK506-based regulation of biological events - Google Patents FK506-based regulation of …
- FK506-based regulation of biological events - Google Patents FK506-based regulation of …
Antibodies, variable domains and chains tailored for human use
The invention relates to the provision of antibody therapeutics and prophylactics that are
tailored specifically for human use. The present invention provides libraries, vertebrates and …
tailored specifically for human use. The present invention provides libraries, vertebrates and …
Animal models and therapeutic molecules
The invention discloses methods for the generation of chimaeric human-non-human
antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and …
antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and …
Humanized dipeptidyl peptidase IV (DPP4) animals
C Kyratsous, A Mujica - US Patent 9,497,945, 2016 - Google Patents
2015/0351372 Al 12/2015 Kyratsous et al. elements is also provided, including non-human
animals that have a replacement of non-human Dpp4-encoding sequence with human …
animals that have a replacement of non-human Dpp4-encoding sequence with human …