Rho signaling research: history, current status and future directions
S Narumiya, D Thumkeo - FEBS letters, 2018 - Wiley Online Library
One of the main research areas in biology from the mid‐1980s through the 1990s was the
elucidation of signaling pathways governing cell responses. These studies brought, among …
elucidation of signaling pathways governing cell responses. These studies brought, among …
[HTML][HTML] The ras superfamily of small gtpases in non-neoplastic cerebral diseases
L Qu, C Pan, SM He, B Lang, GD Gao… - Frontiers in molecular …, 2019 - frontiersin.org
The small GTPases from the Ras superfamily play crucial roles in basic cellular processes
during practically the entire process of neurodevelopment, including neurogenesis …
during practically the entire process of neurodevelopment, including neurogenesis …
[HTML][HTML] Training-induced circuit-specific excitatory synaptogenesis in mice is required for effort control
Synaptogenesis is essential for circuit development; however, it is unknown whether it is
critical for the establishment and performance of goal-directed voluntary behaviors. Here, we …
critical for the establishment and performance of goal-directed voluntary behaviors. Here, we …
Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior
Depression alters the structure and function of brain reward circuitry. Preclinical evidence
suggests that medium spiny neurons (MSNs) in the nucleus accumbens (NAc) undergo …
suggests that medium spiny neurons (MSNs) in the nucleus accumbens (NAc) undergo …
A hippocampo-cortical pathway detects changes in the validity of an action as a predictor of reward
R Piquet, A Faugère, SL Parkes - Current Biology, 2024 - cell.com
Much research has been dedicated to understanding the psychological and neural bases of
goal-directed action, yet the relationship between context and goal-directed action is not …
goal-directed action, yet the relationship between context and goal-directed action is not …
Dendritic spine dynamics in associative memory: A comprehensive review
Associative learning and memory are fundamental behavioral processes through which
organisms adapt to complex environments. Associative memory involves long‐lasting …
organisms adapt to complex environments. Associative memory involves long‐lasting …
[HTML][HTML] Long-term memory, synaptic plasticity and dopamine in rodent medial prefrontal cortex: Role in executive functions
Mnemonic functions, supporting rodent behavior in complex tasks, include both long-term
and (short-term) working memory components. While working memory is thought to rely on …
and (short-term) working memory components. While working memory is thought to rely on …
Social isolation in adolescence disrupts cortical development and goal-dependent decision-making in adulthood, despite social reintegration
The social environment influences neurodevelopment. Investigations using rodents to study
this phenomenon commonly isolate subjects, then assess neurobehavioral consequences …
this phenomenon commonly isolate subjects, then assess neurobehavioral consequences …
Involvement of the rodent prelimbic and medial orbitofrontal cortices in goal‐directed action: A brief review
Goal‐directed action refers to selecting behaviors based on the expectation that they will be
reinforced with desirable outcomes. It is typically conceptualized as opposing habit‐based …
reinforced with desirable outcomes. It is typically conceptualized as opposing habit‐based …
Making and breaking habits: Revisiting the definitions and behavioral factors that influence habits in animals
SN Handel, RJ Smith - Journal of the Experimental Analysis of …, 2024 - Wiley Online Library
Habits have garnered significant interest in studies of associative learning and maladaptive
behavior. However, habit research has faced scrutiny and challenges related to the …
behavior. However, habit research has faced scrutiny and challenges related to the …