Biofilms in diabetic foot ulcers: significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

Biofilm-innate immune interface: contribution to chronic wound formation

Z Versey, WS da Cruz Nizer, E Russell, S Zigic… - Frontiers in …, 2021 - frontiersin.org
Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …

The microbiology of diabetic foot infections: a meta-analysis

KE Macdonald, S Boeckh, HJ Stacey, JD Jones - BMC infectious diseases, 2021 - Springer
Background Diabetic foot ulcers are a common complication of poorly controlled diabetes
and often become infected, termed diabetic foot infection. There have been numerous …

Biofilms in diabetic foot ulcers: impact, risk factors and control strategies

AC Afonso, D Oliveira, MJ Saavedra, A Borges… - International journal of …, 2021 - mdpi.com
Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …

Diagnosis and management of diabetic foot complications

AJM Boulton, DG Armstrong, RS Kirsner, CE Attinger… - 2018 - Am Diabetes Assoc
At least half of all amputations occur in people with diabetes, most commonly because of an
infected diabetic foot ulcer. A thorough understanding of the causes and management of …

A review on revolutionary natural biopolymer-based aerogels for antibacterial delivery

EB Yahya, F Jummaat, AA Amirul, AS Adnan… - Antibiotics, 2020 - mdpi.com
A biopolymer-based aerogel has been developed to become one of the most potentially
utilized materials in different biomedical applications. The biopolymer-based aerogel has …

Bioactive injectable hydrogel dressings for bacteria-infected diabetic wound healing: a “pull–push” approach

K Zhang, C Yang, C Cheng, C Shi, M Sun… - … applied materials & …, 2022 - ACS Publications
Chronic diabetic wound healing remains a challenge due to the existence of excessive
danger molecules and bacteria in the inflammatory microenvironment. There is an urgent …

Antibiotic resistance and biofilm tolerance: a combined threat in the treatment of chronic infections

PG Bowler - Journal of Wound Care, 2018 - magonlinelibrary.com
Since the introduction of antibiotics into human medicine in the 1940's, antibiotic resistance
has emerged at an alarming rate and is now a major threat to public health. This problem is …

[HTML][HTML] Wound microenvironment-responsive glucose consumption and hydrogen peroxide generation synergistic with azithromycin for diabetic wounds healing

M Shi, Z Du, Y Qi, W Li, H Hu, X Lin, S Wang, Z Tang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Chronic wounds are one of the common complications of diabetes. Due to the
physiological conditions of diabetic patients, these wounds are more susceptible to bacterial …

Colonizing microbiota is associated with clinical outcomes in diabetic wound healing

G Wang, Z Lin, Y Li, L Chen, SK Reddy, Z Hu… - Advanced drug delivery …, 2023 - Elsevier
With the development of society and the improvement of life quality, more than 500 million
people are affected by diabetes. More than 10% of people with diabetes will suffer from …