Gram-negative bacteria and lipopolysaccharides as risk factors for the occurrence of diabetic foot

S Zhang, S Li, J Huang, X Ding, Y Qiu… - The Journal of …, 2023 - academic.oup.com
Context Imbalance of the skin microbial community could impair skin immune homeostasis
and thus trigger skin lesions. Dysbiosis of skin microbiome may be involved in the early …

Catalase-templated nanozyme-loaded microneedles integrated with polymyxin B for immunoregulation and antibacterial activity in diabetic wounds

G Cai, R Li, X Chai, X Cai, K Zheng, Y Wang… - Journal of Colloid and …, 2024 - Elsevier
Diabetic wounds are characterized by chronic trauma, with long-term non-healing attributed
to persistent inflammation and recurrent bacterial infections. Exacerbation of the …

[HTML][HTML] Four in one—Combination therapy using live Lactococcus lactis expressing three therapeutic proteins for the treatment of chronic non-healing wounds

J Kurkipuro, I Mierau, T Wirth, H Samaranayake… - PLoS …, 2022 - journals.plos.org
Diabetes mellitus is one of the major concerns for health care systems, affecting 382 million
people worldwide. Among the different complications of diabetes, lower limbs chronic …

[HTML][HTML] Multi-Instrumental Analysis Toward Exploring the Diabetic Foot Infection Microbiota

M Złoch, E Maślak, W Kupczyk, P Pomastowski - Current Microbiology, 2023 - Springer
The polymicrobial nature of diabetic foot infection (DFI) makes accurate identification of the
DFI microbiota, including rapid detection of drug resistance, challenging. Therefore, the …

Molecular Characteristics of Staphylococcus aureus Strains Isolated from Nasal Cavity and Wound Infections Among Diabetic Patients

E Taki, F Jabalameli, MRM Tehrani, MM Feizabadi… - Current …, 2023 - Springer
Staphylococcus aureus is the most common pathogen contributing to diabetic foot infections
(DFI). Nasal transmission of S. aureus potentially increases the risk of endogenous infection …

[HTML][HTML] Adaptation of Staphylococcus aureus in a Medium Mimicking a Diabetic Foot Environment

C Pouget, CA Gustave, C Ngba-Essebe, F Laurent… - Toxins, 2021 - mdpi.com
Staphylococcus aureus is the most prevalent pathogen isolated from diabetic foot infections
(DFIs). The purpose of this study was to evaluate its behavior in an in vitro model mimicking …

Ex situ model of biofilm‐associated wounds: providing a host‐like environment for the study of Staphylococcus aureus and Pseudomonas aeruginosa biofilms

GMM Guedes, ASP Santos‐Filho… - Journal of Applied …, 2021 - academic.oup.com
Aim This study aimed to assess an ex situ model of biofilm‐associated wounds on porcine
skin for the study of Staphylococcus aureus and Pseudomonas aeruginosa biofilms in a host …

Clinical impact of an anti-biofilm Hydrofiber dressing in hard-to-heal wounds previously managed with traditional antimicrobial products and systemic antibiotics

DG Metcalf, PG Bowler - Burns & Trauma, 2020 - academic.oup.com
Background Hard-to-heal wounds are often compromised by the presence of biofilm. This
presents an infection risk, yet traditional antimicrobial wound care products and systemic …

Opisthorchiasis and the Microbiome

IV Saltykova, VA Petrov, PJ Brindley - Advances in parasitology, 2018 - Elsevier
The liver flukes Opisthorchis viverrini, O. felineus, and Clonorchis sinensis are closely
related fish-borne trematodes endemic in East Asia, Eurasia, and Siberia. Following …

Microbiome imbalances: an overlooked potential mechanism in chronic nonhealing wounds

M Pang, M Zhu, X Lei, P Xu… - The International Journal …, 2019 - journals.sagepub.com
Chronic nonhealing wounds are a severe burden to health care systems worldwide, causing
millions of patients to have lengthy hospital stays, high health care costs, periods of …