Ethnopharmacology has been an important starting point in medical and pharmaceutical
sciences for discovering drug candidates from natural sources. In this regard, the genus …

Alzheimer's disease (AD) is a multifactorial, rapidly progressing neurodegenerative disorder.
As the exact cause of the disease is still unclear, the drug development is very challenging …

Microglia are necessary for central nervous system (CNS) function during development and
play roles in ageing, Alzheimer's disease and the response to demyelinating injury,,,–. The …

Idebenone is an analogue of coenzyme Q10, an electron donor in the mitochondrial electron
transport chain, and thus may function as an antioxidant to facilitate mitochondrial function …

Abstract Background Amyloid-β1-42 (Aβ1-42) plays an essential role in the development of
the early stage of Alzheimer's disease (AD). Asiatic acid (AA), an active compound in …

Transgenic models of familial Alzheimer's disease (AD) serve as valuable tools for probing
the molecular mechanisms associated with amyloid-beta (Aβ)-induced pathology. In this …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder resulting in cognitive
decline or dementia, the number of patients with AD is continuously increasing. Although a …

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder, characterized by
memory deficit and dementia. AD is considered a multifactorial disorder where multiple …

The relationship between the two most prominent neuropathological hallmarks of
Alzheimer's Disease (AD), extracellular amyloid-β (Aβ) deposits and intracellular …

Recent studies have implicated impaired Parvalbumin Fast-Spiking Interneuron (PVIN)
function as a precipitating factor underlying abnormalities in network synchrony, oscillatory …