SARS-CoV-2 variants, vaccines, and host immunity

P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …

Defining trained immunity and its role in health and disease

MG Netea, J Domínguez-Andrés, LB Barreiro… - Nature Reviews …, 2020 - nature.com
Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers …

Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing

W Wen, W Su, H Tang, W Le, X Zhang, Y Zheng, X Liu… - Cell discovery, 2020 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, has recently affected over 1,200,000 people
and killed more than 60,000. The key immune cell subsets change and their states during …

Neuroinflammation and depression: A review

R Troubat, P Barone, S Leman… - European journal of …, 2021 - Wiley Online Library
Some recent clinical and preclinical evidence suggests that neuroinflammation is a key
factor that interacts with the three neurobiological correlates of major depressive disorder …

Probiotics regulate gut microbiota: an effective method to improve immunity

X Wang, P Zhang, X Zhang - Molecules, 2021 - mdpi.com
Probiotics are beneficial active microorganisms that colonize the human intestines and
change the composition of the flora in particular parts of the host. Recently, the use of …

Immunology of aging: the birth of inflammaging

T Fulop, A Larbi, G Pawelec, A Khalil, AA Cohen… - Clinical reviews in …, 2021 - Springer
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

[HTML][HTML] The interplay between the gut microbiome and the immune system in the context of infectious diseases throughout life and the role of nutrition in optimizing …

SP Wiertsema, J van Bergenhenegouwen, J Garssen… - Nutrients, 2021 - mdpi.com
Infectious diseases and infections remain a leading cause of death in low-income countries
and a major risk to vulnerable groups, such as infants and the elderly. The immune system …

Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice

NYL Pang, ASR Pang, VT Chow, DY Wang - Military Medical Research, 2021 - Springer
SARS-CoV-2 is a newly identified member of the coronavirus family that has caused the
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting …

[HTML][HTML] Mucins in intestinal mucosal defense and inflammation: learning from clinical and experimental studies

JA Grondin, YH Kwon, PM Far, S Haq… - Frontiers in …, 2020 - frontiersin.org
Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly
glycosylated proteins called mucins plays an essential role in providing lubrication for the …

The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics

L Qian, X Lin, X Gao, RU Khan, JY Liao, S Du… - Chemical …, 2023 - ACS Publications
The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …