Caffeine is a naturally occurring alkaloid found in various plants. It acts as a stimulant,
antioxidant, anti-inflammatory, and even an aid in pain management, and is found in several …

Neurodegenerative diseases (NDs) encompass a broad range of conditions characterized
by progressive neuronal degeneration and death and manifesting with a variety of signs and …

The occurrence of wounds and defects in the healing process is one of the main challenges
in diabetic patients. Herein, we investigated whether adipose-derived stem cells (ADSCs) …

Background Identifying effective spinal cord injury (SCI) treatments remains a major
challenge, and current approaches are still unable to effectively improve its. Currently, we …

Due to the multifactorial nature of diabetic wounds, the most effective treatments require
combinatorial approach. Herein we investigated whether engraftment of a bioengineered …

Acute kidney injury is one of the most threatening diseases in neonates, with complex
pathogenesis and limited treatment options. Caffeine is a commonly used central nervous …

The most important factors in the non-optimal healing of diabetic wounds are the lack of a
suitable scaffold in the wound site for the migration and replacement of cells, as well as the …

One of the most common complications of chronic scrotal hyperthermia (SHT) is a serious
disorder in the male reproductive system. The most important factor in the occurrence of …

Spinal cord injury (SCI) following trauma is a devastating neurological event that can lead to
loss of sensory and motor functions. However, the most effective measures to prevent the …

Tramadol and tapentadol are chemically related opioids prescribed for the analgesia of
moderate to severe pain. Although safer than classical opioids, they are associated with …