Identification of cytotoxic T cell epitopes within Epstein‐Barr virus (EBV) oncogene latent membrane protein 1 (LMP1): evidence for HLA A2 supertype‐restricted …

R Khanna, SR Burrows, J Nicholls… - European journal of …, 1998 - Wiley Online Library
Epstein‐Barr virus (EBV) nuclear antigen 1 (EBNA1) and latent membrane proteins (LMP)
are the only antigens consistently expressed in malignancies such as nasopharyngeal …

T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen.

SR Burrows, SL Silins, DJ Moss, R Khanna… - The Journal of …, 1995 - rupress.org
Two unusual characteristics of the memory response to the immunodominant Epstein-Barr
virus (EBV) epitope FLRGRAYGL, which associates with HLA B8, have provided an unique …

Epstein-Barr virus-latent gene expression and tumor cell phenotype in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. Correlation of …

SJ Hamilton-Dutoit, D Rea, M Raphael… - The American journal …, 1993 - ncbi.nlm.nih.gov
We investigated 49 acquired immunodeficiency syndrome-related lymphomas (ARLs) for
Epstein-Barr virus (EBV) by Southern blotting and in situ hybridization and, in positive cases …

Cross‐reactive memory T cells for Epstein‐Barr virus augment the alloresponse to common human leukocyte antigens: degenerate recognition of major …

SR Burrows, SL Silins, R Khanna… - European journal of …, 1997 - Wiley Online Library
In the present report, cytotoxic T lymphocyte (CTL) clones are described that display dual
specificity for one of two common human leukocyte antigens (HLA B14 or B35) as …

An Epstein-Barr virus-specific cytotoxic T cell epitope in EBV nuclear antigen 3 (EBNA 3).

SR Burrows, TB Sculley, IS Misko, C Schmidt… - The Journal of …, 1990 - rupress.org
Epstein-Barr virus (EBV)-specific CTL clones were isolated that recognized A-type EBV
transformants but not B-type transformants. These A-type-specific CTL clones (HLA B8 …

Coinfection with a and B-type Epstein-Barr virus in human immunodeficiency virus-positive subjects

TB Sculley, A Apolloni, L Hurren… - Journal of Infectious …, 1990 - academic.oup.com
A possible cofactor in human immunodeficiency virus (HIV) infection is the Epstein-Barr virus
(EBV), which is divided into two primary types that differ significantly in their transformation …

Epstein‐Barr virus‐infected B cells persist in the circulation of acyclovir‐treated virus carriers

QY Yao, P Ogan, M Rowe, M Wood… - … Journal of Cancer, 1989 - Wiley Online Library
In this study, infectious Epstein‐Barr virus (EBV) shedding in the oropharynx and numbers of
virus‐infected B cells in the blood have been monitored in long‐term virus carriers receiving …

Peptide-MHC class I tetrameric complexes display exquisite ligand specificity

SR Burrows, N Kienzle, A Winterhalter… - The Journal of …, 2000 - journals.aai.org
The production of synthetic MHC-peptide tetramers has revolutionized cellular immunology
by revealing enormous CD8+ T cell expansions specific for peptides from various …

Molecular epidemiology of Epstein–Barr virus infection

JW Gratama, I Ernberg - Advances in cancer research, 1995 - Elsevier
Publisher Summary This chapter discusses the information obtained by the molecular
characterization of Epstein–Barr virus (EBV) diversity and explains its relevance for viral …

Vaccine strategies against Epstein‐Barr virus‐associated diseases: lessons from studies on cytotoxic T‐cell‐mediated immune regulation

R Khanna, DJ Moss, SR Burrows - Immunological reviews, 1999 - Wiley Online Library
Development of a vaccine against Epstein‐Barr virus (HBV) is constrained by the latency
phenotypes adopted by different EBV‐associated diseases. Over the last few years an …