Vaccine strategies against Epstein‐Barr virus‐associated diseases: lessons from studies on cytotoxic T‐cell‐mediated immune regulation

R Khanna, DJ Moss, SR Burrows - Immunological reviews, 1999 - Wiley Online Library
Development of a vaccine against Epstein‐Barr virus (HBV) is constrained by the latency
phenotypes adopted by different EBV‐associated diseases. Over the last few years an …

Epstein-Barr virus and the lacrimal gland pathology of Sjögren's syndrome.

SC Pflugfelder, CA Crouse, D Monroy… - The American journal …, 1993 - ncbi.nlm.nih.gov
The lacrimal gland (LG) immunopathology of Sjögren's syndrome (SS) consists of a
proliferation of B and CD4 lymphocytes surrounding epithelial structures (Pepose JS, et al …

Influence of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virus

C Rooney, JG Howe, SH Speck, G Miller - Journal of virology, 1989 - Am Soc Microbiol
The Epstein-Barr virus (EBV) genes expressed in B lymphocytes immortalized in vitro or in
Burkitt's lymphoma (BL) cells infected in vivo have been characterized previously; however …

Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide.

JM Brooks, RJ Murray, WA Thomas… - The Journal of …, 1993 - rupress.org
An immunological basis has been postulated for the strong association between at least five
subtypes of the HLA-B27 allele (B27. 01,. 02,. 04,. 05, and. 06) and ankylosing spondylitis …

MYC overexpression imposes a nonimmunogenic phenotype on Epstein–Barr virus-infected B cells

MS Staege, SP Lee, T Frisan… - Proceedings of the …, 2002 - National Acad Sciences
Lymphoblastoid cell lines, generated by immortalization of normal B cells by Epstein–Barr
virus (EBV) in vitro, have strong antigen-presenting capacity, are sensitive to EBV-specific …

Correlation of the expression of Epstein-Barr virus latent membrane protein and in situ hybridization with biotinylated BamHI-W probes in Hodgkin's disease.

G Delsol, P Brousset, S Chittal… - The American journal of …, 1992 - ncbi.nlm.nih.gov
Abstract The detection of Epstein-Barr virus (EBV) nucleic acids by in situ hybridization (ISH)
with biotinylated BamHI-W probes was correlated with the expressions of EBV latent …

EBV structural antigens, gp350 and gp85, as targets for ex vivo virus-specific CTL during acute infectious mononucleosis: potential use of gp350/gp85 CTL epitopes …

R Khanna, M Sherritt, SR Burrows - The Journal of Immunology, 1999 - journals.aai.org
For many years, EBV vaccine development efforts have concentrated on the use of structural
Ag, gp350, and have been directed toward Ab-mediated blocking virus attachment to the …

Recognition of the Epstein-Barr virus-encoded nuclear antigens EBNA-4 and EBNA-6 by HLA-A11-restricted cytotoxic T lymphocytes: implications for down-regulation …

R Gavioli, PO De Campos-Lima… - Proceedings of the …, 1992 - National Acad Sciences
Evasion from cytotoxic T-lymphocyte (CTL) surveillance may be an important step in the
pathogenesis of Epstein-Barr virus (EBV)-carrying Burkitt lymphoma (BL) as suggested by …

The immunology of Epstein–Barr virus infection

DJ Moss, SR Burrows, SL Silins… - … Transactions of the …, 2001 - royalsocietypublishing.org
Epstein–Barr virus is a classic example of a persistent human virus that has caught the
imagination of immunologists, virologists and oncologists because of the juxtaposition of a …

Exclusive expression of Epstein-Barr virus nuclear antigen 1 in Burkitt lymphoma arises from a third promoter, distinct from the promoters used in latently infected …

BC Schaefer, M Woisetschlaeger… - Proceedings of the …, 1991 - National Acad Sciences
Epstein-Barr virus transformation of human B lymphocytes in vitro results in the expression
of six viral nuclear antigens (EBNAs) and three viral membrane proteins. However …