Dendrimers as pharmaceutical excipients: synthesis, properties, toxicity and biomedical applications

A Santos, F Veiga, A Figueiras - Materials, 2019 - mdpi.com
The European Medicines Agency (EMA) and the Current Good Manufacturing Practices
(cGMP) in the United States of America, define excipient as the constituents of the …

Poly (propylene imine) dendrimer as an emerging polymeric nanocarrier for anticancer drug and gene delivery

V Singh, A Sahebkar, P Kesharwani - European Polymer Journal, 2021 - Elsevier
Dendrimers are well-defined globular macromolecules with multiple polymeric branching
that are amenable to undergo structural modifications. This property makes dendrimers …

Dendrimer as nanocarrier for drug delivery

P Kesharwani, K Jain, NK Jain - Progress in Polymer Science, 2014 - Elsevier
Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …

Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

K Madaan, S Kumar, N Poonia, V Lather… - Journal of Pharmacy …, 2014 - journals.lww.com
Dendrimers are the emerging polymeric architectures that are known for their defined
structures, versatility in drug delivery and high functionality whose properties resemble with …

Dendrimer toxicity: Let's meet the challenge

K Jain, P Kesharwani, U Gupta, NK Jain - International journal of …, 2010 - Elsevier
Dendrimers are well-defined, versatile polymeric architecture with properties resembling
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine …

Dendrimers as efficient nanocarriers for the protection and delivery of bioactive phytochemicals

M Yousefi, A Narmani, SM Jafari - Advances in colloid and interface science, 2020 - Elsevier
The genesis of dendrimers can be considered as a revolution in nano-scaled bioactive
delivery systems. These structures possess a unique potential in encapsulating/entrapping …

A review of nanocarriers for the delivery of small interfering RNA

P Kesharwani, V Gajbhiye, NK Jain - Biomaterials, 2012 - Elsevier
Increasing knowledge about molecular mechanisms of endogenous RNA interference
(RNAi) and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic …

Research status of dendrimer micelles in tumor therapy for drug delivery

X Wang, M Zhang, Y Li, H Cong, B Yu, Y Shen - Small, 2023 - Wiley Online Library
Dendrimers are a family of polymers with highly branched structure, well‐defined
composition, and extensive functional groups, which have attracted great attention in …

Drug delivery strategies for poorly water-soluble drugs

A Fahr, X Liu - Expert opinion on drug delivery, 2007 - Taylor & Francis
The drug candidates coming from combinatorial chemistry research and/or the drugs
selected from biologically based high-throughput screening are quite often very lipophilic, as …

Impact of dendrimers on solubility of hydrophobic drug molecules

S Choudhary, L Gupta, S Rani, K Dave… - Frontiers in …, 2017 - frontiersin.org
Adequate aqueous solubility has been one of the desired properties while selecting drug
molecules and other bio-actives for product development. Often solubility of a drug …