Dendrimers as pharmaceutical excipients: synthesis, properties, toxicity and biomedical applications
The European Medicines Agency (EMA) and the Current Good Manufacturing Practices
(cGMP) in the United States of America, define excipient as the constituents of the …
(cGMP) in the United States of America, define excipient as the constituents of the …
Poly (propylene imine) dendrimer as an emerging polymeric nanocarrier for anticancer drug and gene delivery
V Singh, A Sahebkar, P Kesharwani - European Polymer Journal, 2021 - Elsevier
Dendrimers are well-defined globular macromolecules with multiple polymeric branching
that are amenable to undergo structural modifications. This property makes dendrimers …
that are amenable to undergo structural modifications. This property makes dendrimers …
Dendrimer as nanocarrier for drug delivery
P Kesharwani, K Jain, NK Jain - Progress in Polymer Science, 2014 - Elsevier
Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …
Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues
Dendrimers are the emerging polymeric architectures that are known for their defined
structures, versatility in drug delivery and high functionality whose properties resemble with …
structures, versatility in drug delivery and high functionality whose properties resemble with …
Dendrimer toxicity: Let's meet the challenge
Dendrimers are well-defined, versatile polymeric architecture with properties resembling
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine …
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine …
Dendrimers as efficient nanocarriers for the protection and delivery of bioactive phytochemicals
The genesis of dendrimers can be considered as a revolution in nano-scaled bioactive
delivery systems. These structures possess a unique potential in encapsulating/entrapping …
delivery systems. These structures possess a unique potential in encapsulating/entrapping …
A review of nanocarriers for the delivery of small interfering RNA
P Kesharwani, V Gajbhiye, NK Jain - Biomaterials, 2012 - Elsevier
Increasing knowledge about molecular mechanisms of endogenous RNA interference
(RNAi) and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic …
(RNAi) and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic …
Research status of dendrimer micelles in tumor therapy for drug delivery
X Wang, M Zhang, Y Li, H Cong, B Yu, Y Shen - Small, 2023 - Wiley Online Library
Dendrimers are a family of polymers with highly branched structure, well‐defined
composition, and extensive functional groups, which have attracted great attention in …
composition, and extensive functional groups, which have attracted great attention in …
Drug delivery strategies for poorly water-soluble drugs
A Fahr, X Liu - Expert opinion on drug delivery, 2007 - Taylor & Francis
The drug candidates coming from combinatorial chemistry research and/or the drugs
selected from biologically based high-throughput screening are quite often very lipophilic, as …
selected from biologically based high-throughput screening are quite often very lipophilic, as …
Impact of dendrimers on solubility of hydrophobic drug molecules
Adequate aqueous solubility has been one of the desired properties while selecting drug
molecules and other bio-actives for product development. Often solubility of a drug …
molecules and other bio-actives for product development. Often solubility of a drug …