Amorphous solid dispersions (ASDs), in which polymers are admixed with a drug, retard or
inhibit crystallization of the drug, increasing the drug's apparent solubility and oral …

The primary focus of the research is to study the role of cocrystal and amorphous solid
dispersion approaches for enhancing solubility and preserving the stability of a poorly …

Crystallization inhibitors in amorphous solid dispersions (ASD) enable metastable
supersaturated drug solutions that persist for a physiologically relevant time. Olefin cross …

Glimepiride is an antidiabetic drug which is one of the third generation sulfonylureas. It
belongs to class II, according to the BCS (Biopharmaceutical Classification System), which is …

There has been recent interest in using hydroxypropyl cellulose (HPC) for supersaturating
drug formulations. This study investigated the potential for molecular HPC interactions with …

Abstract Development of new approaches for oral delivery of an existing antiviral drug aimed
to enhance its permeability and hence bioavailability. Ganciclovir (GC) is an antiviral drug …

Naringin (NAR), a major flavanone (FVA) glycoside, is a component of food mainly obtained
from grapefruit. We used NAR as a food additive to improve the solubility and permeability of …

Amorphous solid dispersions (ASDs) are commonly used to orally deliver small-molecule
drugs that are poorly water-soluble. ASDs consist of drug molecules in the amorphous form …

This article takes a step forward in understanding the mechanisms involved during the
preparation and performance of cross-linked high-drug-loading (HDL) amorphous solid …

The impact of residual drug crystals that are formed during the production and storage of
amorphous solid dispersions (ASDs) has been studied using micron-sized seed crystals in …