The implications of autoimmunity and pregnancy

AT Borchers, SM Naguwa, CL Keen… - Journal of autoimmunity, 2010 - Elsevier
There are multiple epidemiological studies that document the potential adverse affects of
autoimmunity on nearly every aspect of reproduction, even in the absence of clinically …

Seronegative antiphospholipid syndrome

R Nayfe, I Uthman, J Aoun, E Saad Aldin… - …, 2013 - academic.oup.com
APS is an autoimmune disease that leads to arterial and/or venous thrombosis, recurrent
pregnancy loss and persistently positive aPLs. Patients with clinical manifestations highly …

Pregnancy loss and thrombophilia: the elusive link

SA Bennett, CN Bagot, R Arya - British journal of haematology, 2012 - Wiley Online Library
Recurrent pregnancy loss (RPL) affects 1% pregnancies and is multi‐factorial in origin. The
role of the acquired thrombophilia antiphospholipid syndrome (APS) as a common and …

Anti-annexins autoantibodies: their role as biomarkers of autoimmune diseases

L Iaccarino, A Ghirardello, M Canova, M Zen… - Autoimmunity …, 2011 - Elsevier
Annexins are a group of 12 highly conserved proteins which exert several regulatory
functions on cell biology. There are involved in numerous cell processes including vesicle …

Anti-beta2-glycoprotein I: prevalence, clinical correlations, and importance of persistent positivity in patients with antiphospholipid syndrome and systemic lupus …

A Danowski, TS Kickler, M Petri - The Journal of rheumatology, 2006 - jrheum.org
OBJECTIVE: Antibodies to beta2-glycoprotein I (anti-beta2-GPI) are found in a large
percentage of patients with primary or secondary antiphospholipid syndrome (APS). Our aim …

Non-conventional antiphospholipid antibodies in patients with clinical obstetrical APS: Prevalence and treatment efficacy in pregnancies

A Mekinian, MC Bourrienne, L Carbillon… - Seminars in arthritis and …, 2016 - Elsevier
Objectives To describe the prevalence of non-conventional APL in patients with obstetrical
APS without conventional APL and the impact of treatment on pregnancy outcome. Methods …

New autoantigens in the antiphospholipid syndrome

C Alessandri, F Conti, M Pendolino, R Mancini… - Autoimmunity …, 2011 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by arterial
and venous thrombosis, recurrent miscarriages or fetal loss, and circulating antiphospholipid …

Thrombotic risk assessment in antiphospholipid syndrome: the role of new antibody specificities and thrombin generation assay

S Sciascia, S Baldovino, K Schreiber, L Solfietti… - Clinical and Molecular …, 2016 - Springer
Antiphospholipid syndrome (APS) is an autoimmune condition characterized by the
presence of antiphospholipid antibodies (aPL) in subjects presenting with thrombosis and/or …

Annexin A5 polymorphism (− 1C→ T) and the presence of anti-annexin A5 antibodies in the antiphospholipid syndrome

B de Laat, RHWM Derksen, IJ Mackie… - Annals of the …, 2006 - ard.bmj.com
Background: Annexin A5 is thought to have a role in the pathophysiology of the
antiphospholipid syndrome (APS)—a syndrome characterised by recurrent thrombosis and …

[HTML][HTML] The anticardiolipin assay is required for sensitive screening for antiphospholipid antibodies

MJ Nash, RS Camilleri, S Kunka, IJ Mackie… - Journal of thrombosis …, 2004 - Elsevier
The importance of testing for anticardiolipin antibodies (aCL) in the diagnosis of
antiphospholipid syndrome (APS) in patients with thrombosis has recently been challenged …