The distributed genome hypothesis as a rubric for understanding evolution in situ during chronic bacterial biofilm infectious processes

GD Ehrlich, A Ahmed, J Earl, NL Hiller… - FEMS Immunology & …, 2010 - academic.oup.com
Most chronic infectious disease processes associated with bacteria are characterized by the
formation of a biofilm that provides for bacterial attachment to the host tissue or the …

[HTML][HTML] Challenges and promises for planning future clinical research into bacteriophage therapy against Pseudomonas aeruginosa in cystic fibrosis. An …

M Rossitto, EV Fiscarelli, P Rosati - Frontiers in microbiology, 2018 - frontiersin.org
Although early aggressive and prolonged treatment with specific antibiotics can extend
survival in patients with cystic fibrosis (CF) colonized by opportunistic Pseudomonas …

[HTML][HTML] Sequence and functional analyses of Haemophilusspp. genomic islands

M Juhas, PM Power, RM Harding, DJP Ferguson… - Genome biology, 2007 - Springer
Background A major part of horizontal gene transfer that contributes to the diversification
and adaptation of bacteria is facilitated by genomic islands. The evolution of these islands is …

Pseudomonas aeruginosa and Staphylococcus aureus communication in biofilm infections: insights through network and database construction

AP Magalhães, P Jorge, MO Pereira - Critical reviews in …, 2019 - Taylor & Francis
The polymicrobial nature of most infections is often characterized by complex biofilm
communities, where pathogen interactions promote infection progression and severity …

Genomic islands of Pseudomonas aeruginosa

SE Battle, J Rello, AR Hauser - FEMS microbiology letters, 2009 - academic.oup.com
Key to Pseudomonas aeruginosa's ability to thrive in a diversity of niches is the presence of
numerous genomic islands that confer adaptive traits upon individual strains. We reasoned …

[HTML][HTML] What makes pathogens pathogenic

GD Ehrlich, NL Hiller, FZ Hu - Genome biology, 2008 - Springer
Metazoans contain multiple complex microbial ecosystems in which the balance between
host and microbe can be tipped from commensalism to pathogenicity. This transition is likely …

The role of prophage in plant-pathogenic bacteria

AM Varani, CB Monteiro-Vitorello… - Annual review of …, 2013 - annualreviews.org
A diverse set of phage lineages is associated with the bacterial plant-pathogen genomes
sequenced to date. Analysis of 37 genomes revealed 5,169 potential genes (approximately …

[HTML][HTML] A Genetic Approach to the Development of New Therapeutic Phages to Fight Pseudomonas Aeruginosa in Wound Infections

V Krylov, O Shaburova, S Krylov, E Pleteneva - Viruses, 2012 - mdpi.com
Pseudomonas aeruginosa is a frequent participant in wound infections. Emergence of
multiple antibiotic resistant strains has created significant problems in the treatment of …

Rhizospheric and endophytic Pseudomonas aeruginosa in edible vegetable plants share molecular and metabolic traits with clinical isolates

S Ambreetha, P Marimuthu, K Mathee… - Journal of Applied …, 2022 - academic.oup.com
Aim Pseudomonas aeruginosa, a leading opportunistic pathogen causing hospital‐acquired
infections, is also commonly found in agricultural settings. However, there are minimal …

[HTML][HTML] Towards understanding Pseudomonas aeruginosa burn wound infections by profiling gene expression

P Bielecki, J Glik, M Kawecki… - Biotechnology letters, 2008 - Springer
Pseudomonas aeruginosa is a key opportunistic pathogen causing severe acute and
chronic nosocomial infections in immunocompromised or catheterized patients. It is …