Caveolae are submicroscopic, plasma membrane pits that are abundant in many
mammalian cell types. The past few years have seen a quantum leap in our understanding …

It has been over 20 years since the discovery that caveolar lipid rafts function as signalling
organelles. Lipid rafts create plasma membrane heterogeneity, and caveolae are the most …

Caveolins (Cavs) are~ 20 kDa scaffolding proteins that assemble as oligomeric complexes
in lipid raft domains to form caveolae, flask-shaped plasma membrane (PM) invaginations …

Abstract Caveolin-1 (Cav1) is an integral membrane, scaffolding protein found in plasma
membrane invaginations (caveolae). Cav1 regulates multiple cancer-associated processes …

Cellular senescence is a feature of most somatic cells. It is characterized by an irreversible
cell cycle arrest and by the ability to secrete a plethora of mediators of inflammation and …

Caveolae are non‐clathrin invaginations of the plasma membrane in most cell types; they
are involved in signalling functions and molecule trafficking, thus modulating several …

Abstract Caveolin-1 (Cav-1) is both a tumor suppressor and an oncoprotein. Cav-1
overexpression was frequently confirmed in advanced cancer stages and positively …

Caveolin-1 (CAV1) is a membrane-sculpting protein that oligomerizes to generate flask-
shaped invaginations of the plasma membrane known as caveolae. Mutations in CAV1 have …

Caveolae are bulb-like invaginations made up of two essential structural proteins, caveolin-
1 and cavins, which are abundantly present at the plasma membrane of vertebrate cells …

In addition to containing highly dynamic nanoscale domains, the plasma membranes of
many cell types are decorated with caveolae, flask-shaped domains enriched in the …