Aging is associated with a low-grade, systemic inflammatory state defined as
“inflammaging”, ruled by the loss of proper regulation of the immune system leading to the …

There is growing interest in interventions that delay, slow, and even reverse frailty. In this
narrative review, we explore the evidence on exercise, nutrition, medication optimisation …

Therapy for Parkinson's disease is quite challenging. Numerous drugs are available for
symptomatic treatment, and levodopa (LD), in combination with a dopa decarboxylase …

Importance Older adults with atopic dermatitis (AD) face unique treatment challenges,
including comorbidities, polypharmacy, and a higher risk for infections (eg, herpes zoster) …

Background: Few studies have examined the epidemiology of polypharmacy in non-
institutionalized elderly adults with regard to sex differences. This study aimed to identify the …

Abstract Background and Objective Prescribing cascades occur when a drug is prescribed
to manage side effects of another drug, typically when a side effect is misinterpreted as a …

Gendered ageism: addressing discrimination based on age and sex - The Lancet Skip to Main
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Background Polypharmacy is one of the most important health issues for its potential
impacts on disease burden and healthcare costs. The aim of this study was to update a …

Background Deprescribing is essential for reducing inappropriate medication use and
polypharmacy. For a holistic approach, it is essential to know how older adult patients and …

Prescribing cascades are increasingly recognized since they were described in the mid-
1990s. Cascades are more likely in older people with multimorbidity and associated …