Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics

A Chamoli, AS Gosavi, UP Shirwadkar, KV Wangdale… - Oral oncology, 2021 - Elsevier
Oral cavity squamous cell carcinoma (OCSCC) is the most common malignancy of the oral
cavity. The substantial risk factors for OCSCC are the consumption of tobacco products …

[HTML][HTML] Tongue carcinoma in young adults: a review of the literature

A Paderno, R Morello, C Piazza - Acta Otorhinolaryngologica …, 2018 - ncbi.nlm.nih.gov
SUMMARY A recent reduction in the number of smoke-related tumours has been observed
thanks to the diffusion of anti-tobacco campaigns carried out in the majority of developed …

[HTML][HTML] Chromosomal alterations and gene expression changes associated with the progression of leukoplakia to advanced gingivobuccal cancer

PG Bhosale, S Cristea, S Ambatipudi, RS Desai… - Translational …, 2017 - Elsevier
We present an integrative genome-wide analysis that can be used to predict the risk of
progression from leukoplakia to oral squamous cell carcinoma (OSCC) arising in the …

[HTML][HTML] DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment …

HY Lin, SK Hung, MS Lee, WY Chiou, TT Huang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Radioresistance is still an emerging problem for radiotherapy of oral cancer. Aberrant
epigenetic alterations play an important role in cancer development, yet the role of such …

[HTML][HTML] Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients

A Knopf, J Lempart, M Bas, J Slotta-Huspenina… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Objectives The occurrence of squamous cell carcinoma of the tongue (SCCT) of young
patients increased. There are still controversies about patient prognosis. The underlying …

[HTML][HTML] MFI2 upregulation promotes malignant progression through EGF/FAK signaling in oral cavity squamous cell carcinoma

WC Yen, KP Chang, CY Chen, Y Huang… - Cancer Cell …, 2023 - Springer
Oral squamous cell carcinoma (OSCC) is the predominant histological type of the head and
neck squamous cell carcinoma (HNSCC). By comparing the differentially expressed genes …

[HTML][HTML] Prognostic significance of decreased expression of six large common fragile site genes in oropharyngeal squamous cell carcinomas

G Gao, JL Kasperbauer, NM Tombers, MD Cornell… - Translational …, 2014 - Elsevier
Common fragile sites (CFSs) are large regions with profound genomic instability that often
span extremely large genes a number of which have been found to be important tumor …

喉鳞癌组织中脆性组氨酸三联体基因和增殖蛋白的关系

刘瑶, 崔颖, 刘卫芳 - 中国老年学杂志, 2016 - cqvip.com
目的检测喉鳞癌中脆性组氨酸三联体基因(FHIT), 增殖细胞核抗原(PCNA) 和Ki67
增殖蛋白(Ki67) 的表达特征, 探讨FHIT 对增殖的作用. 方法67 例喉鳞癌患者的临床资料和术后 …

[HTML][HTML] FHIT down-regulation was inversely linked to aggressive behaviors and adverse prognosis of gastric cancer: a meta-and bioinformatics analysis

HC Zheng, LL Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
FHIT (fragile histine triad) acts as diadenosine P1, P3-bis (5'-adenosyl)-triphosphate
adenylohydrolase involved in purine metabolism, and induces apoptosis as a tumor …

[HTML][HTML] Chromosomal aberrations and prognosis in patients with concomitant chemoradiotherapy for resected head and neck cancer

SW Park, YH Joo, SH Jung, SH Yim… - Oncology …, 2016 - spandidos-publications.com
Although concomitant chemoradiotherapy (CCRT) has recently become a mainstay of a
primary treatment modality in advanced head and neck squamous cell carcinoma (HNSCC) …