Genetic, developmental, biochemical, and environmental variables interact intricately to
produce sex differences. The significance of sex differences in cancer susceptibility is being …

Several medications and medication classes have been reported to affect the lipid profile.
Risk factors include elevated lipid levels at baseline and high cardiovascular (CV) risk …

The nuclear receptor (NR) class of transcription factors controls critical regulatory events in
key developmental processes, homeostasis maintenance, and medically important diseases …

Clinically, girls appear to be more sensitive than boys to the cardiotoxic effects of
doxorubicin, whereas the opposite may be true for adults. To identify and characterize …

Abstract Background/Aims: Estrogen treatment is thought to lower low-density lipoprotein
(LDL) cholesterol levels by increasing clearance through hepatic LDL receptors. This study …

The maximum therapeutic potentials of pharmacologically active molecules are generally
not attained due to their non specific delivery. Ligands associated with drug or delivery …

Homeobox gene HOXB9 is a critical player in development of mammary gland and sternum
and in regulation of renin which is closely linked with blood pressure control. Our studies …

There is still controversy as to whether estrogen inhibits or enhances heat-shock protein
(HSP72) expression in the heart. To evaluate the gender difference, whole-body …

Abstract Purpose Chemotherapy with doxorubicin (Dox) causes dose-limiting cardiotoxicity.
We investigated the role that gender has on cardiosensitivity to Dox treatment by evaluating …

Purpose: Thermotolerance is an acquired state of increased cytoprotection achieved
following single or repeated exposures to heat stress, in part characterized by changes in …