Background Cardiac fibrogenesis in the late stage of viral myocarditis causing contractile
dysfunction and ventricular dilatation, is a major pathogenic factor for the progression of …

Background & Aims How benign liver steatosis progresses to nonalcoholic steatohepatitis
(NASH), fibrosis, and hepatocellular carcinoma (HCC) remains elusive. NASH progression …

Acute-on-chronic liver failure (ACLF) is a severe life-threatening condition with high risk of
multiorgan failure, sepsis, and mortality. ACLF activates a multifaceted interplay of both …

Summary Interleukin-22 (IL-22) is a vital cytokine that is dysregulated in various autoimmune
conditions including rheumatoid arthritis (RA), multiple sclerosis (MS), and Alzheimer's …

Purpose: To conduct a narrative review of research articles on the potential anti-and pro-
fibrotic mechanisms of noncoding RNAs following glaucoma filtration surgery. Methods …

ABSTRACT Interleukin 22 (IL-22) is an IL-10-related cytokine produced by T helper 17
(Th17) cells and other immune cells that signals via IL-22 receptor alpha 1 (IL-22Ra1) …

AIM To explore the effect of interleukin (IL)-22 on in vitro model of alcoholic liver fibrosis
hepatic stellate cells (HSCs), and whether this is related to regulation of Nrf2-keap1-ARE …

The three main causes of inflammation and chronic injury in the liver are viral hepatitis,
alcohol consumption, and non-alcoholic steatohepatitis, all of which can lead to liver fibrosis …

Immune-mediated liver injury is widely seen during hepatitis B virus (HBV) infection.
Unsuccessful immune clearance of HBV results in chronic hepatitis and increases the risk of …

Interleukin-22 (IL-22) is a Th17 cell hepatoprotective cytokine that is undergoing clinical
trials to treat patients with alcoholic hepatitis (AH). Lipopolysaccharide (LPS) activation of …