Identification of trypsin-degrading commensals in the large intestine

Y Li, E Watanabe, Y Kawashima, DR Plichta, Z Wang… - Nature, 2022 - nature.com
Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in
intestinal pathological conditions,–. However, the players and mechanisms that underlie …

Isolation and infection cycle of a polinton-like virus virophage in an abundant marine alga

S Roitman, A Rozenberg, T Lavy, CPD Brussaard… - Nature …, 2023 - nature.com
Virophages are small double stranded DNA (dsDNA) viruses that can only replicate in a host
by co-infecting with another virus. Marine algae are commonly associated with virophage …

[PDF][PDF] High dietary sugar reshapes sweet taste to promote feeding behavior in Drosophila melanogaster

CE May, A Vaziri, YQ Lin, O Grushko, M Khabiri… - Cell reports, 2019 - cell.com
Recent studies find that sugar tastes less intense to humans with obesity, but whether this
sensory change is a cause or a consequence of obesity is unclear. To tackle this question …

Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia

M Guellil, L van Dorp, SA Inskip, JM Dittmar, L Saag… - Science …, 2022 - science.org
Human herpes simplex virus 1 (HSV-1), a life-long infection spread by oral contact, infects a
majority of adults globally. Phylogeographic clustering of sampled diversity into European …

[PDF][PDF] Shifts in the genetic landscape of the western Eurasian steppe associated with the beginning and end of the Scythian dominance

M Järve, L Saag, CL Scheib, AK Pathak, F Montinaro… - Current Biology, 2019 - cell.com
Summary The Early Iron Age nomadic Scythians have been described as a confederation of
tribes of different origins, based on ancient DNA evidence [1–3]. It is still unclear how much …

Divergent evolutionary trajectories following speciation in two ectoparasitic honey bee mites

MA Techer, RV Rane, ML Grau, JMK Roberts… - Communications …, 2019 - nature.com
Multispecies host-parasite evolution is common, but how parasites evolve after speciating
remains poorly understood. Shared evolutionary history and physiology may propel species …

An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim

M Guellil, M Keller, JM Dittmar, SA Inskip, C Cessford… - Genome biology, 2022 - Springer
Abstract Background The human pathogen Haemophilus influenzae was the main cause of
bacterial meningitis in children and a major cause of worldwide infant mortality before the …

RNase H genes cause distinct impacts on RNA: DNA hybrid formation and mutagenesis genome wide

JW Schroeder, RL Hurto, JR Randall, KJ Wozniak… - Science …, 2023 - science.org
RNA: DNA hybrids compromise replication fork progression and genome integrity in all cells.
The overall impacts of naturally occurring RNA: DNA hybrids on genome integrity, and the …

[PDF][PDF] Museum genomics confirms that the Lord Howe Island stick insect survived extinction

AS Mikheyev, A Zwick, MJL Magrath, ML Grau, L Qiu… - Current Biology, 2017 - cell.com
Summary The Lord Howe Island stick insect, Dryococelus australis, was once common on
the island but was driven to extinction after the arrival of ship rats in the early 20 th century …

Improvement of the Pacific bluefin tuna (Thunnus orientalis) reference genome and development of male-specific DNA markers

A Suda, I Nishiki, Y Iwasaki, A Matsuura, T Akita… - Scientific reports, 2019 - nature.com
Abstract The Pacific bluefin tuna, Thunnus orientalis, is a highly migratory species that is
widely distributed in the North Pacific Ocean. Like other marine species, T. orientalis has no …