Hyperammonemia resulting from inherited urea cycle enzyme deficiencies or liver failure
results in severe central nervous system dysfunction including brain edema, convulsions …

Ammonia is an unusual toxicant in that it is produced by, as well as being poisonous to,
animals. In aqueous solution ammonia has two species, NH 3 and NH 4+, total ammonia is …

The economics of most modern aquaculture operations require that animals be cultured at
high densities. A consequence of high‐density aquaculture is the increased probability that …

Rats were made chronically hyperammonemic by portal-systemic shunting and, 8 wk later,
were subjected to acute ammonia intoxication by the intraperitoneal injection of 5.2 mmol/kg …

The cerebral tricarboxylic acid (TCA) cycle rate and the rate of glutamine synthesis were
measured in rats in vivo under normal physiological and hyperammonemic conditions using …

Both basic and clinical aspects are stressed, including the biochemical, anatomic,
physiologic, and pathologic. Emphasis is on the diagnosis and treatment of liver disease …

Ammonia is considered the main agent responsible for the neurological alterations in
hepatic encephalopathy. It was suggested that ammonia toxicity is mediated by activation of …

Fiber is not digested by endogenous enzymes but is fermented by microbes principally in
the large intestine. With fermentable energy available, microbes synthesize protein by using …

Exposure to acutely lethal un‐ionised ammonia concentrations resulted in a 3.3‐fold
increase in oxygen consumption. This was associated with increases in ventilation volume …

Salmo gairdneri specimens were exposed for 4–48 hr to various environmental un-ionized
ammonia (UIA) concentrations. In the brain of NH 3-treated trout glutamate, GABA, total …