Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

The Role of TNF-α in Alzheimer's Disease: A Narrative Review

D Plantone, M Pardini, D Righi, C Manco, BM Colombo… - Cells, 2023 - mdpi.com
This review analyzes the role of TNF-α and its increase in biological fluids in mild cognitive
impairment, and Alzheimer's disease (AD). The potential inhibition of TNF-α with …

[HTML][HTML] Pre-pregnancy obesity is associated with greater systemic inflammation and increased risk of antenatal depression

L Sominsky, M O'Hely, K Drummond, S Cao… - Brain, Behavior, and …, 2023 - Elsevier
Background Pre-pregnancy obesity is an emerging risk factor for perinatal depression.
However, the underlying mechanisms remain unclear. We investigated the association …

The putative role of neuroinflammation in the interaction between traumatic brain injuries, sleep, pain and other neuropsychiatric outcomes: a state-of-the-art review

A Herrero Babiloni, AA Baril… - Journal of clinical …, 2023 - mdpi.com
Sleep disturbances are widely prevalent following a traumatic brain injury (TBI) and have the
potential to contribute to numerous post-traumatic physiological, psychological, and …

Is obstructive sleep apnea a circadian rhythm disorder?

J Šmon, E Kočar, T Pintar… - Journal of sleep …, 2023 - Wiley Online Library
Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …

Dietary marine hydrolysate improves memory performance and social behavior through gut microbiota remodeling during aging

C Mougin, M Chataigner, C Lucas, Q Leyrolle, V Pallet… - Foods, 2023 - mdpi.com
Aging is characterized by a decline in social behavior and cognitive functions leading to a
decrease in life quality. In a previous study, we show that a fish hydrolysate supplementation …

Physical activity as a promising alternative for young people with juvenile idiopathic arthritis: Towards an evidence-based prescription

E Rochette, O Saidi, É Merlin, P Duché - Frontiers in Immunology, 2023 - frontiersin.org
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in young people.
Although biologics now enable most children and adolescents with JIA to enjoy clinical …

[HTML][HTML] Postinfectious inflammation, autoimmunity, and obsessive-compulsive disorder: sydenham chorea, pediatric autoimmune neuropsychiatric disorder …

A Vreeland, D Calaprice, N Or-Geva, RE Frye… - Developmental …, 2023 - karger.com
Postinfectious neuroinflammation has been implicated in multiple models of acute-onset
obsessive-compulsive disorder including Sydenham chorea (SC), pediatric acute-onset …

Circadian variation in stroke onset: differences between ischemic and hemorrhagic stroke and weekdays versus weekends

F Pariona-Vargas, KT Mun, EH Lo, S Starkman… - Journal of Stroke and …, 2023 - Elsevier
Objectives To delineate diurnal variation onset distinguishing ischemic from hemorrhagic
stroke, wake from sleep onset, and weekdays from weekends/holidays. Materials and …

Long-term PM2. 5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models

S Hao, Z Chen, Y Gu, L Chen, F Sheng, Y Xu… - Particle and Fibre …, 2023 - Springer
Background Limbal stem/progenitor cells (LSPCs) play a crucial role in maintaining corneal
health by regulating epithelial homeostasis. Although PM2. 5 is associated with the …