Organs-on-a-chip: a union of tissue engineering and microfabrication

Y Zhao, EY Wang, FBL Lai, K Cheung, M Radisic - Trends in biotechnology, 2023 - cell.com
We review the emergence of the new field of organ-on-a-chip (OOAC) engineering, from the
parent fields of tissue engineering and microfluidics. We place into perspective the tools and …

Adipose‐derived stem cells for tissue engineering and regenerative medicine applications

R Dai, Z Wang, R Samanipour, K Koo… - Stem cells …, 2016 - Wiley Online Library
Adipose‐derived stem cells (ASCs) are a mesenchymal stem cell source with properties of
self‐renewal and multipotential differentiation. Compared to bone marrow‐derived stem …

Engineering complex tissues

A Atala, FK Kasper, AG Mikos - Science translational medicine, 2012 - science.org
Tissue engineering has emerged at the intersection of numerous disciplines to meet a
global clinical need for technologies to promote the regeneration of functional living tissues …

Dermal matrices and bioengineered skin substitutes: a critical review of current options

H Debels, M Hamdi, K Abberton… - … Surgery–Global Open, 2015 - journals.lww.com
Background: Over recent decades, scientists and surgeons have collaborated to develop
various bioengineered and synthetic products as an alternative to skin grafts. Despite the …

[HTML][HTML] Commercialization and regulation of regenerative medicine products: Promises, advances and challenges

N Beheshtizadeh, M Gharibshahian… - Biomedicine & …, 2022 - Elsevier
The ultimate goal of regenerative medicine is to repair, regenerate, or reconstruct functional
loss in failed tissues and/or organs. Although regenerative medicine is a relatively new field …

Tissue matrix arrays for high-throughput screening and systems analysis of cell function

VZ Beachley, MT Wolf, K Sadtler, SS Manda… - Nature …, 2015 - nature.com
Cell and protein arrays have demonstrated remarkable utility in the high-throughput
evaluation of biological responses; however, they lack the complexity of native tissue and …

Progress in the tissue engineering and stem cell industry “are we there yet?”

A Jaklenec, A Stamp, E Deweerd… - … Engineering Part B …, 2012 - liebertpub.com
This report presents a detailed update to our 2008 publication on the tissue engineering
(TE) and stem cell industry. Data are reported through mid 2011 showing an almost three …

Bioreactors in tissue engineering—principles, applications and commercial constraints

J Hansmann, F Groeber, A Kahlig… - Biotechnology …, 2013 - Wiley Online Library
Bioreactor technology is vital for tissue engineering. Usually, bioreactors are used to provide
a tissue‐specific physiological in vitro environment during tissue maturation. In addition to …

Epithelial and stromal developmental patterns in a novel substitute of the human skin generated with fibrin-agarose biomaterials

V Carriel, I Garzón, JM Jiménez, ACX Oliveira… - Cells Tissues …, 2012 - karger.com
Abstract Development of human skin substitutes by tissue engineering may offer new
therapeutic alternatives to the use of autologous tissue grafts. For that reason, it is necessary …

Recent advances in the regenerative approaches for traumatic spinal cord injury: materials perspective

WA Abbas, ME Ibrahim, M El-Naggar… - ACS Biomaterials …, 2020 - ACS Publications
Spinal cord injury (SCI) is a devastating health condition that may lead to permanent
disabilities and death. Understanding the pathophysiological perspectives of traumatic SCI …