Bone marrow: The central immune system

V Schirrmacher - Immuno, 2023 - mdpi.com
Bone marrow is known as the site of hematopoiesis. What is not being described in
textbooks of immunology is the fact that bone marrow is not only a generative, but also an …

Refined control of CRISPR-Cas9 gene editing in Clostridium sporogenes: the creation of recombinant strains for therapeutic applications

AM Kubiak, L Claessen, Y Zhang, K Khazaie… - Frontiers in …, 2023 - frontiersin.org
Despite considerable clinical success, the potential of cancer immunotherapy is restricted by
a lack of tumour-targeting strategies. Treatment requires systemic delivery of cytokines or …

CD44 targeted delivery of oncolytic Newcastle disease virus encapsulated in thiolated Chitosan for sustained release in cervical cancer: a targeted immunotherapy …

K Kousar, F Naseer, MS Abduh, S Anjum… - Frontiers in …, 2023 - frontiersin.org
Introduction Cervical cancer accounts for one of most common cancers among women of
reproductive age. Oncolytic virotherapy has emerged as a promising immunotherapy …

Individualized multimodal immunotherapy for adults with IDH1 wild-type GBM: A single institute experience

SW Van Gool, J Makalowski, P Van de Vliet… - Cancers, 2023 - mdpi.com
Simple Summary The standard of care for patients with primary glioblastoma multiforme
consists of neurosurgery, radiochemotherapy, and maintenance chemotherapy. We added …

Individualized Multimodal Immunotherapy (IMI): Scientific Rationale and Clinical Experience from a Single Institution

V Schirrmacher, S Van Gool, W Stuecker - Biomedicines, 2024 - mdpi.com
Oncolytic viruses and combinatorial immunotherapy for cancer (this Special Issue) are both
part of cancer treatment at IOZK. This review focusses on an individual multimodal cancer …

Methods behind oncolytic virus-based DC vaccines in cancer: Toward a multiphase combined treatment strategy for Glioblastoma (GBM) patients.

SW Van Gool, P Van de Vliet, LFC Kampers… - Methods in Cell …, 2023 - europepmc.org
Glioblastoma (GBM) remains an orphan cancer disease with poor outcome. Novel treatment
strategies are needed. Immunotherapy has several modes of action. The addition of active …

[HTML][HTML] Interconnection and Communication between Bone Marrow-The Central Immune System-And the Central Nervous System

V Schirrmacher - Journal of Neuroscience and Neurological …, 2023 - neuroscijournal.com
Bone marrow and the central nervous system are both protected by bone. The two systems
are interconnected not only structurally but also functionally. In both systems specialized …

[HTML][HTML] The Role of Newcastle Disease Virus in Cancer Therapy: A Systematic Review

N Rajaei, N Faraji, PB Khabaz, M Yousefi… - Journal of World's …, 2023 - cyberleninka.ru
Recently, immunotherapy has become a hopeful option for cancer therapy. Taking
advantage of pathogens is a well-established method of cancer immunotherapy. It has been …

[PDF][PDF] Stefaan W. Van Gool∗, Peter Van de Vliet, Linde FC Kampers, Jennifer Kosmal, Tobias Sprenger, Ella Reich

V Schirrmacher, W Stuecker - 2023 - dght-ev.de
Glioblastoma (GBM) remains an orphan cancer disease with poor outcome. Novel treatment
strategies are needed. Immunotherapy has several modes of action. The addition of active …

[PDF][PDF] Kousain Kousar1, Faiza Naseer1, 2, Maisa Siddiq Abduh3, 4, Sadia Anjum5 and Tahir Ahmad1

K Kousar, T Ahmad, K Kousar, F Naseer, MS Abduh… - 2023 - researchgate.net
Methods: Using half dose of NDV (TCID50 (50% tissue culture infective dose) single dose
3× 105), virus loaded nanoparticles were prepared by green synthesis approach through …