[HTML][HTML] Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: the role of Epstein–Barr virus and the gut–brain axis

K Hashimoto - Molecular Psychiatry, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …

[HTML][HTML] The role of viral infections in the onset of autoimmune diseases

B Sundaresan, F Shirafkan, K Ripperger, K Rattay - Viruses, 2023 - mdpi.com
Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

[HTML][HTML] Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019

D Wu, Y Jin, Y Xing, MD Abate, M Abbasian… - …, 2023 - thelancet.com
Background The causes for immune-mediated inflammatory diseases (IMIDs) are diverse
and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to …

Locus for severity implicates CNS resilience in progression of multiple sclerosis

MultipleMS Consortium Harroud Adil 1 78 78 Jónsdóttir … - Nature, 2023 - nature.com
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that
results in significant neurodegeneration in the majority of those affected and is a common …

[HTML][HTML] Antibody cross-reactivity in auto-immune diseases

NH Trier, G Houen - International Journal of Molecular Sciences, 2023 - mdpi.com
Autoimmunity is defined by the presence of antibodies and/or T cells directed against self-
components. Although of unknown etiology, autoimmunity commonly is associated with …

Vaccines for immune tolerance against autoimmune disease

A Kim, F Xie, OA Abed, JJ Moon - Advanced drug delivery reviews, 2023 - Elsevier
The high prevalence and rising incidence of autoimmune diseases have become a
prominent public health issue. Autoimmune disorders result from the immune system …

[HTML][HTML] Chitinase signature in the plasticity of neurodegenerative diseases

C Russo, MS Valle, A Casabona… - International Journal of …, 2023 - mdpi.com
Several reports have pointed out that Chitinases are expressed and secreted by various cell
types of central nervous system (CNS), including activated microglia and astrocytes. These …

Anti‐EBV antibodies: Roles in diagnosis, pathogenesis, and antiviral therapy

C Xie, LY Zhong, GL Bu, GX Zhao… - Journal of Medical …, 2023 - Wiley Online Library
Epstein‐Barr virus (EBV) infection is prevalent in global population and associated with
multiple malignancies and autoimmune diseases. During the infection, EBV‐harbored or …

[HTML][HTML] Review of multiple sclerosis: Epidemiology, etiology, pathophysiology, and treatment

M Haki, HA Al-Biati, ZS Al-Tameemi, IS Ali… - Medicine, 2024 - journals.lww.com
Multiple sclerosis (MS) is a chronic autoimmune disease with demyelination, inflammation,
neuronal loss, and gliosis (scarring). Our object to review MS pathophysiology causes and …

[HTML][HTML] The contribution of microglia and brain-infiltrating macrophages to the pathogenesis of neuroinflammatory and neurodegenerative diseases during TMEV …

AB DePaula-Silva - Viruses, 2024 - mdpi.com
The infection of the central nervous system (CNS) with neurotropic viruses induces
neuroinflammation and is associated with the development of neuroinflammatory and …