Background Female genital schistosomiasis (FGS) affects up to 56 million women in sub-
Saharan Africa and may increase risk of HIV infection. Methods To assess the association of …

Infections caused by parasitic flatworms impose a considerable worldwide health burden.
One of the most impactful is schistosomiasis, a disease caused by parasitic blood flukes …

The anthelmintic drug praziquantel (PZQ) is used to treat schistosomiasis, a neglected
tropical disease that affects over 200 million people worldwide. PZQ causes Ca 2+ influx …

Schistosomiasis is one of the most prominent parasite-induced infectious diseases, causing
tremendous medical and socioeconomic problems. Current studies have reported on the …

Only praziquantel is available for treating schistosomiasis, a disease affecting more than
200 million people. Praziquantel-resistant worms have been selected for in the lab and low …

Background Hormonal changes during the menstrual cycle play a key role in shaping
immunity in the cervicovaginal tract. Cervicovaginal fluid contains cytokines, chemokines …

Schistosomiasis is a neglected tropical disease caused by the helminth Schistosoma spp.
and has the second highest global impact of all parasites. Schistosoma are transmitted …

Although a growing number of studies suggest interactions between Schistosoma parasites
and viral infections, the effects of schistosome infections on the host response to viruses …

Human immunodeficiency virus (HIV) remains a leading cause of global morbidity with the
highest burden in Sub-Saharan Africa (SSA). For reasons that are incompletely understood …

HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high
HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female …