Skin microbiota: a source of disease or defence?
Microbes found on the skin are usually regarded as pathogens, potential pathogens or
innocuous symbiotic organisms. Advances in microbiology and immunology are revising our …
innocuous symbiotic organisms. Advances in microbiology and immunology are revising our …
Directed evolution of enzymes for industrial biocatalysis
JL Porter, RA Rusli, DL Ollis - ChemBioChem, 2016 - Wiley Online Library
Enzymes have the potential to catalyse a wide variety of chemical reactions. They are
increasingly being sought as environmentally friendly and cost‐effective alternatives to …
increasingly being sought as environmentally friendly and cost‐effective alternatives to …
Proteases as therapeutics
CS Craik, MJ Page, EL Madison - Biochemical Journal, 2011 - portlandpress.com
Proteases are an expanding class of drugs that hold great promise. The US FDA (Food and
Drug Administration) has approved 12 protease therapies, and a number of next generation …
Drug Administration) has approved 12 protease therapies, and a number of next generation …
Understanding the immunogenicity and antigenicity of nanomaterials: Past, present and future
AN Ilinskaya, MA Dobrovolskaia - Toxicology and applied pharmacology, 2016 - Elsevier
Nanoparticle immunogenicity and antigenicity have been under investigation for many
years. During the past decade, significant progress has been made in understanding what …
years. During the past decade, significant progress has been made in understanding what …
A deep learning based data driven soft sensor for bioprocesses
V Gopakumar, S Tiwari, I Rahman - Biochemical engineering journal, 2018 - Elsevier
Developing accurate and robust sensors for nonlinear and highly varying systems is a
challenge. Deep learning, an advanced technique to learn deep architectures, has become …
challenge. Deep learning, an advanced technique to learn deep architectures, has become …
The biochemical and physical process of fibrinolysis and effects of clot structure and stability on the lysis rate
JW Weisel, RI Litvinov - Cardiovascular & Hematological …, 2008 - ingentaconnect.com
The effectiveness of fibrinolysis results from the combination of regulated enzymatic activity
and the physical properties of the fibrin scaffold. Physiologically, clots or thrombi are …
and the physical properties of the fibrin scaffold. Physiologically, clots or thrombi are …
Leonurine Ameliorates Oxidative Stress and Insufficient Angiogenesis by Regulating the PI3K/Akt‐eNOS Signaling Pathway in H2O2‐Induced HUVECs
L Liao, L Gong, M Zhou, X Xue, Y Li… - Oxidative medicine and …, 2021 - Wiley Online Library
Thrombus is considered to be the pathological source of morbidity and mortality of
cardiovascular disease and thrombotic complications, while oxidative stress is regarded as …
cardiovascular disease and thrombotic complications, while oxidative stress is regarded as …
The evolution of recombinant thrombolytics: Current status and future directions
Adivitiya, YP Khasa - Bioengineered, 2017 - Taylor & Francis
Cardiovascular disorders are on the rise worldwide due to alcohol abuse, obesity,
hypertension, raised blood lipids, diabetes and age-related risks. The use of classical …
hypertension, raised blood lipids, diabetes and age-related risks. The use of classical …
A critical review on marine serine protease and its inhibitors: A new wave of drugs?
Marine organisms are rich sources of enzymes and their inhibitors having enormous
therapeutic potential. Among different proteolytic enzymes, serine proteases, which can be …
therapeutic potential. Among different proteolytic enzymes, serine proteases, which can be …
The molecular basis of thrombolysis and its clinical application in stroke
V Murray, B Norrving, PAG Sandercock… - Journal of internal …, 2010 - Wiley Online Library
Murray V, Norrving B, Sandercock PAG, Terént A, Wardlaw JM, Wester P (Karolinska
Institutet Danderyd Hospital, Stockholm; Department of Neurology, Lund, Sweden; Division …
Institutet Danderyd Hospital, Stockholm; Department of Neurology, Lund, Sweden; Division …